Gay M. Crooks

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

Nathalia Holt, Jianbin Wang, Kenneth Kim et al. · Nature Biotechnology · 2010 · 676 citations

Life Sciences, Hematology, Molecular Biology +11

Engraftment of gene–modified umbilical cord blood cells in neonates with adenosine deaminase deficiency

Donald B. Kohn, Kenneth I. Weinberg, Jan A. Nolta et al. · Nature Medicine · 1995 · 611 citations · Full text

Pharmacy, Molecular Biology, Pediatrics +15

Stable transduction of quiescent CD34 ⁺ CD38 ⁻ human hematopoietic cells by HIV-1-based lentiviral vectors

Scott S. Case, Mary Ann Price, Craig T. Jordan et al. · Proceedings of the National Academy of Sciences · 1999 · 394 citations

Life Sciences, Cell Biology, Molecular Biology +13

T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates

Donald B. Kohn, Michal S. Hershfield, Denise A. Carbonaro et al. · Nature Medicine · 1998 · 331 citations · Full text

Life Sciences, Genetics, Immunology +14

Generation of mature T cells from human hematopoietic stem and progenitor cells in artificial thymic organoids

Christopher S. Seet, Chongbin He, Michael T. Bethune et al. · Nature Methods · 2017 · 268 citations · Full text

Life Sciences, Cell Biology, Immunology +17