Concepedia

Statistical Hit Selection

Statistical Hit Selection is a methodological framework in high-throughput screening that identifies compounds or entities exhibiting significant biological activity by applying statistical criteria to distinguish true effects from random variation.

16

Publications

1.1K

Citations

66

Authors

32

Institutions

Publications per year

2017–2026

1

Parents

Publications

16

Improved Statistical Methods for Hit Selection in High-Throughput Screening

Christine Brideau, Bert Gunter, Bill Pikounis et al. · SLAS DISCOVERY · 2003 · 341 citations · Full text

, , +8

Illustration of SSMD, z Score, SSMD*, z* Score, and t Statistic for Hit Selection in RNAi High-Throughput Screens

Xiaohua Douglas Zhang · SLAS DISCOVERY · 2011 · 211 citations · Full text

, , +12

Robust Statistical Methods for Hit Selection in RNA Interference High-Throughput Screening Experiments

Xiaohua Douglas Zhang, Xiting Cindy Yang, Namjin Chung et al. · Pharmacogenomics · 2006 · 103 citations

, , +16

The Use of Strictly Standardized Mean Difference for Hit Selection in Primary RNA Interference High-Throughput Screening Experiments

Xiaohua Douglas Zhang, Marc Ferrer, Amy S. Espeseth et al. · SLAS DISCOVERY · 2007 · 101 citations · Full text

, , +14

Identifying Actives from HTS Data Sets: Practical Approaches for the Selection of an Appropriate HTS Data-Processing Method and Quality Control Review

Tong Ying Shun, John S. Lazo, Elizabeth R. Sharlow et al. · SLAS DISCOVERY · 2010 · 78 citations

, , +16

1–5 of 16

Authors

66

  1. XD
    Xiaohua Douglas Zhang

    University of Macau, Macao SAR China

    5 publications · 473 citations

    5

    h-index

  2. MF
    Marc Ferrer

    National Center for Advancing Translational Sciences, United States

    3 publications · 240 citations

    3

    h-index

  3. JF
    Joseph F. Heyse

    United States Military Academy, United States

    2 publications · 137 citations

    2

    h-index

  4. SM
    Shane Marine

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    2 publications · 137 citations

    2

    h-index

  5. ES
    Erica Stec

    Merck & Co., Inc., Rahway, NJ, USA (United States), United States

    2 publications · 204 citations

    2

    h-index

1–5 of 66

Institutions

32

  1. United States Military Academy

    West Point, United States

    5 h-index

    12 publications

    924 citations

  2. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    3 h-index

    14 publications

    969 citations

  3. Environmental Protection Agency

    Washington, United States

    1 h-index

    4 publications

    80 citations

  4. Pfizer (United States)

    New York, United States

    1 h-index

    1 publications

    34 citations

  5. St. Jude Children's Research Hospital

    Memphis, United States

    1 h-index

    3 publications

    51 citations

  6. Zimmer Biomet (Netherlands)

    Dordrecht, Netherlands

    1 h-index

    1 publications

    101 citations

  7. Oak Ridge Associated Universities

    Oak Ridge, United States

    1 h-index

    1 publications

    20 citations

  8. Genomics Institute of the Novartis Research Foundation

    San Diego, United States

    1 h-index

    4 publications

    144 citations

1–8 of 32

Venues

  1. SLAS DISCOVERY

    6 publications · 789 citations

    6

    h-index

  2. MedChemComm

    1 publications · 19 citations

    1

    h-index

  3. PLoS ONE

    1 publications · 17 citations

    1

    h-index

  4. ACS Infectious Diseases

    1 publications · 34 citations

    1

    h-index

  5. Methods in molecular biology

    Book series · 1 publications · 23 citations

    1

    h-index

1–5