Concepedia

Somatic Variant Calling

Somatic Variant Calling is a computational method in variant calling that identifies acquired genetic mutations present in tumor cells but absent in the germline genome of the same individual, distinguishing it from germline variant detection by focusing on somatic alterations associated with cancer development.

108

Publications

16.1K

Citations

966

Authors

304

Institutions

Publications per year

2017–2026

77

Parents

Publications

108

Manta: rapid detection of structural variants and indels for germline and cancer sequencing applications

Xiaoyu Chen, Ole Schulz-Trieglaff, Richard J. Shaw et al. · Bioinformatics · 2015 · 2.4K citations · Full text

, , +17

Absolute quantification of somatic DNA alterations in human cancer

Scott L. Carter, Kristian Cibulskis, Elena Helman et al. · Nature Biotechnology · 2012 · 2.2K citations · Full text

, , +16

Strelka: accurate somatic small-variant calling from sequenced tumor–normal sample pairs

Christopher T. Saunders, Wendy S.W. Wong, Sajani Swamy et al. · Bioinformatics · 2012 · 1.8K citations · Full text

, , +17

Strelka2: fast and accurate calling of germline and somatic variants

Sangtae Kim, Konrad Scheffler, Aaron L. Halpern et al. · Nature Methods · 2018 · 1.8K citations

, , +11

Calling Somatic SNVs and Indels with Mutect2

David Benjamin, Takuto Sato, Kristian Cibulskis et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2019 · 759 citations · Full text

, , +15

1–5 of 108

Authors

966

  1. CT
    Christopher T. Saunders

    Illumina (United States), United States

    4 publications · 6K citations

    4

    h-index

  2. GL
    Gerton Lunter

    University of Oxford, United Kingdom

    3 publications · 155 citations

    3

    h-index

  3. MM
    Marghoob Mohiyuddin

    Stanford University, United States

    3 publications · 331 citations

    3

    h-index

  4. OL
    Obi L. Griffith

    Washington University in St. Louis, United States

    3 publications · 222 citations

    3

    h-index

  5. MK
    Morten Källberg

    Illumina (United Kingdom), United Kingdom

    3 publications · 4.3K citations

    3

    h-index

1–5 of 966

Institutions

304

  1. Washington University in St. Louis

    St Louis, United States

    10 h-index

    42 publications

    5.7K citations

  2. Stanford University

    Stanford, United States

    7 h-index

    26 publications

    1.4K citations

  3. University of California San Diego

    San Diego, United States

    6 h-index

    22 publications

    2.8K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    6 h-index

    45 publications

    10.1K citations

  5. Johns Hopkins University

    Baltimore, United States

    5 h-index

    21 publications

    2.1K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    23 publications

    5.1K citations

  7. University of Oxford

    Oxford, United Kingdom

    5 h-index

    23 publications

    758 citations

  8. Institució Catalana de Recerca i Estudis Avançats

    Barcelona, Spain

    5 h-index

    6 publications

    206 citations

1–8 of 304

Venues

  1. Bioinformatics

    10 publications · 5.2K citations

    10

    h-index

  2. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 13 publications · 1.1K citations

    10

    h-index

  3. Genome biology

    7 publications · 519 citations

    7

    h-index

  4. BMC Bioinformatics

    6 publications · 164 citations

    6

    h-index

  5. PLoS ONE

    5 publications · 390 citations

    5

    h-index

1–5