Concepedia

Absolute quantification of somatic DNA alterations in human cancer

Scott L. Carter, Kristian Cibulskis, Elena Helman, Aaron McKenna, Hui Shen, Travis Zack, Peter W. Laird, Robert C. Onofrio, Wendy Winckler, Barbara A. Weir,

Nature Biotechnology · 2012 · 2.2K citations · 50 references

Open access

Concepts

MedicineGeneticsOncologyCancer GeneticsMolecular OncologyNeoplasiaCancer GenomicsCirculating Tumor Dna AnalysisMalignant NeoplasmsNext-generation Sequencing In OncologySomatic Cell CountSomatic HypermutationAbsolute Dna QuantificationAbsolute QuantificationSomatic Genomic AlterationsSomatic Mutation AnalysisSomatic Mutation ProfilingSomatic MutationsSomatic Variant Calling

References

50

Maximum Likelihood from Incomplete Data Via the <i>EM</i> Algorithm

A. P. Dempster, N. M. Laird, Donald B. Rubin · Journal of the Royal Statistical Society Series B (Statistical Methodology) · 1977 · 49.7K citations

Public Health, Biostatistics, Bayesian Data Analysis +16

Integrated genomic analyses of ovarian carcinoma

Debra Bell, Andrew Berchuck, Narciso Olvera et al. · Nature · 2011 · 8.2K citations · Full text

Medicine, Genetics, Oncology +14

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger, Andrew J. Rowan, Stuart Horswell et al. · New England Journal of Medicine · 2012 · 7.8K citations · Full text

Medicine, Cancer Biology, Oncology +14

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

Medicine, Molecular Genetics, Oncology +12

The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim, Craig H. Mermel, Dale Porter et al. · Nature · 2010 · 4.1K citations · Full text

Medicine, Genetics, Molecular Genetics +14