Elena Helman

Mutational heterogeneity in cancer and the search for new cancer-associated genes

Michael S. Lawrence, Petar Stojanov, Paz Polak et al. · Nature · 2013 · 5.7K citations · Full text

Medicine, Genetics, Oncology +14

Absolute quantification of somatic DNA alterations in human cancer

Scott L. Carter, Kristian Cibulskis, Elena Helman et al. · Nature Biotechnology · 2012 · 2.2K citations · Full text

Medicine, Genetics, Oncology +16

Establishing guidelines to harmonize tumor mutational burden (TMB): in silico assessment of variation in TMB quantification across diagnostic platforms: phase I of the Friends of Cancer Research TMB Harmonization Project

Diana M. Merino, Lisa M. McShane, David Fabrizio et al. · Journal for ImmunoTherapy of Cancer · 2020 · 506 citations · Full text

Medicine, Bioinformatics, Oncology +17

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

Jennifer A. Perry, Adam Kieżun, Peter Tonzi et al. · Proceedings of the National Academy of Sciences · 2014 · 501 citations · Full text

Medicine, Cancer Biology, Oncology +17

<i>BRCA</i> Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma

Kevin Lin, Maria I. Harrell, Amit M. Oza et al. · Cancer Discovery · 2018 · 432 citations

Medicine, Molecular Genetics, Oncology +17