Concepedia

Small-molecule Immunomodulators

Small-Molecule Immunomodulators is a class of pharmacologically active compounds that modulate the activity of the immune system through specific molecular interactions, distinguished by their low molecular weight and capacity to penetrate cellular membranes to exert targeted immunomodulatory effects.

64

Publications

3K

Citations

477

Authors

157

Institutions

Publications per year

2017–2026

17

Parents

Publications

64

Synthesis and Immunosuppressive Activity of 2-Substituted 2-Aminopropane-1,3-diols and 2-Aminoethanols

Masatoshi Kiuchi, Kunitomo Adachi, Toshiyuki Kohara et al. · Journal of Medicinal Chemistry · 2000 · 218 citations

, , +13

A new immunomodulating compound (AS-101) with potential therapeutic application

Benjamin Sredni, Rachel R Caspi, A. Klein et al. · Nature · 1987 · 186 citations

, , +14

Second Near‐Infrared Light‐Activatable Polymeric Nanoantagonist for Photothermal Immunometabolic Cancer Therapy

Cheng Xu, Yuyan Jiang, Jingsheng Huang et al. · Advanced Materials · 2021 · 152 citations

, , +17

Enhancing Adoptive Cell Therapy of Cancer through Targeted Delivery of Small-Molecule Immunomodulators to Internalizing or Noninternalizing Receptors

Yiran Zheng, Li Tang, Llian Mabardi et al. · ACS Nano · 2017 · 147 citations

, , +17

A phase 1/2A Trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohnʼs disease

Robert Burakoff, Charles F. Barish, Dennis Riff et al. · Inflammatory Bowel Diseases · 2006 · 108 citations · Full text

, , +17

1–5 of 64

Authors

477

  1. TS
    Toshihiro Shibata

    Fujisawa City Hospital, Japan

    4 publications · 147 citations

    4

    h-index

  2. HT
    Hiroshi Terano

    Fujisawa City Hospital, Japan

    4 publications · 147 citations

    4

    h-index

  3. PB
    Péter Buchwald

    University of Miami, United States

    3 publications · 88 citations

    3

    h-index

  4. MK
    MASANOBU KOHSAKA

    Fujisawa City Hospital, Japan

    3 publications · 80 citations

    3

    h-index

  5. YT
    YASUHISA TSURUMI

    Fujisawa City Hospital, Japan

    3 publications · 80 citations

    3

    h-index

1–5 of 477

Institutions

157

  1. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    3 h-index

    14 publications

    320 citations

  2. Fujisawa City Hospital

    Fujisawa, Japan

    3 h-index

    18 publications

    480 citations

  3. University of Miami

    Coral Gables, United States

    3 h-index

    15 publications

    474 citations

  4. Chinese Academy of Sciences

    Beijing, China

    3 h-index

    6 publications

    314 citations

  5. Peking University

    Beijing, China

    2 h-index

    10 publications

    552 citations

  6. Astellas Pharma (Japan)

    Tokyo, Japan

    2 h-index

    29 publications

    713 citations

  7. Wuhan University

    Wuhan, China

    2 h-index

    11 publications

    730 citations

  8. Institute of Organic Chemistry

    Warsaw, Poland

    2 h-index

    2 publications

    31 citations

1–8 of 157

Venues

  1. Journal of Medicinal Chemistry

    6 publications · 462 citations

    6

    h-index

  2. PubMed

    Repository · 4 publications · 86 citations

    4

    h-index

  3. The Journal of Antibiotics

    4 publications · 114 citations

    4

    h-index

  4. Bioorganic & Medicinal Chemistry Letters

    3 publications · 149 citations

    3

    h-index

  5. Human Vaccines & Immunotherapeutics

    HV&I · 2 publications · 63 citations

    2

    h-index

1–5