MASANOBU KOHSAKA

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

Toru Kino, Hiroshi Hatanaka, MICHISANE HASHIMOTO et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Biochemistry, Pharmacology +10

FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.

Toru Kino, Hiroshi Hatanaka, Susumu Miyata et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Immunology, Pharmacology +9

Nocardicin a, a new monocyclic .BETA.-lactam antibiotic. I. Discovery, isolation and characterization.

HATSUO AOKI, Heiichi Sakai, MASANOBU KOHSAKA et al. · The Journal of Antibiotics · 1976 · 248 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +7

Discovery of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis.

T Goto, TOHRU KINO, H. Hatanaka et al. · PubMed · 1987 · 218 citations

Pharmacy, Microbiology, Pharmacology +6

Studies of an immunomodulator, swainsonine. I. Enhancement of immune response by swainsonine in vitro.

Motohiro Hino, Osamu Nakayama, YASUHISA TSURUMI et al. · The Journal of Antibiotics · 1985 · 146 citations · Full text

Medicine, Immunology, Pharmacology +5