Concepedia

Small Molecule Reprogramming

Small Molecule Reprogramming is a reprogramming method that employs low molecular weight compounds to modulate cellular signaling pathways and epigenetic states, thereby inducing lineage conversion or pluripotency without genetic manipulation.

10

Publications

1.3K

Citations

104

Authors

40

Institutions

Publications per year

2017–2026

3

Parents

Publications

10

Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons

Xiang Li, Xiaohan Zuo, Junzhan Jing et al. · Cell stem cell · 2015 · 426 citations · Full text

, , +16

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation

Lars Plate, Christina B. Cooley, John J. Chen et al. · eLife · 2016 · 253 citations · Full text

, , +13

Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells

Yohan Kim, Kyojin Kang, Seung Bum Lee et al. · Journal of Hepatology · 2018 · 182 citations

, , +16

Small Molecules Enable Cardiac Reprogramming of Mouse Fibroblasts with a Single Factor, Oct4

Haixia Wang, Nan Cao, C. Ian Spencer et al. · Cell Reports · 2014 · 170 citations · Full text

, , +17

Small molecules facilitate rapid and synchronous iPSC generation

Ori Bar‐Nur, Justin Brumbaugh, Cassandra Verheul et al. · Nature Methods · 2014 · 110 citations · Full text

, , +5

1–5 of 10

Authors

104

  1. SD
    Sheng Ding

    University of California, San Francisco, United States

    2 publications · 196 citations

    2

    h-index

  2. JW
    Jiaming Wang

    Peking University, China

    1 publications · 426 citations

    1

    h-index

  3. YX
    Yan Xia

    Stanford University, United States

    1 publications · 43 citations

    1

    h-index

  4. MS
    Mi‐Young Son

    Korea Research Institute of Bioscience and Biotechnology, South Korea

    1 publications · 43 citations

    1

    h-index

  5. TM
    Tianhua Ma

    University of California, San Francisco, United States

    1 publications · 170 citations

    1

    h-index

1–5 of 104

Institutions

40

  1. University of California, San Francisco

    San Francisco, United States

    3 h-index

    6 publications

    898 citations

  2. Sungkyunkwan University

    Seoul, South Korea

    2 h-index

    4 publications

    215 citations

  3. Korea Advanced Institute of Science and Technology

    Daejeon, South Korea

    2 h-index

    8 publications

    494 citations

  4. Korea Research Institute of Bioscience and Biotechnology

    Daejeon, South Korea

    2 h-index

    9 publications

    412 citations

  5. Korea Institute of Radiological and Medical Sciences

    Seoul, South Korea

    1 h-index

    1 publications

    182 citations

  6. Center for Life Sciences

    Beijing, China

    1 h-index

    11 publications

    4.7K citations

  7. Proteostasis Therapeutics (United States)

    Boston, United States

    1 h-index

    2 publications

    506 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    2 publications

    506 citations

1–8 of 40

Venues

  1. Journal of Hepatology

    1 publications · 182 citations

    1

    h-index

  2. Investigative Ophthalmology & Visual Science

    IOVS · 1 publications · 26 citations

    1

    h-index

  3. eLife

    1 publications · 253 citations

    1

    h-index

  4. Nature Methods

    1 publications · 110 citations

    1

    h-index

  5. Nature Chemical Biology

    1 publications · 68 citations

    1

    h-index

1–5