Concepedia

Slx4 Scaffold Function

SLX4 Scaffold Function is a protein-mediated molecular mechanism that serves as a genomic stability maintenance system by coordinating the assembly and regulation of multiple structure-specific endonucleases at DNA interstrand crosslink sites during repair.

33

Publications

3.5K

Citations

218

Authors

100

Institutions

Publications per year

2017–2026

7

Parents

Publications

33

Mammalian BTBD12/SLX4 Assembles A Holliday Junction Resolvase and Is Required for DNA Repair

Jennifer M. Svendsen, Agata Smogorzewska, Mathew E. Sowa et al. · Cell · 2009 · 451 citations · Full text

, , +10

Human SLX4 Is a Holliday Junction Resolvase Subunit that Binds Multiple DNA Repair/Recombination Endonucleases

Samira Fekairi, Sarah Scaglione, Charly Chahwan et al. · Cell · 2009 · 416 citations · Full text

, , +12

Mutations of the SLX4 gene in Fanconi anemia

Yonghwan Kim, Francis P. Lach, Rohini Desetty et al. · Nature Genetics · 2011 · 375 citations · Full text

, , +13

Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair

Iván Muñoz, Karolina Hain, Anne‐Cécile Déclais et al. · Molecular Cell · 2009 · 335 citations · Full text

, , +14

Coordinated Actions of SLX1-SLX4 and MUS81-EME1 for Holliday Junction Resolution in Human Cells

Haley D.M. Wyatt, Shriparna Sarbajna, Joao Matos et al. · Molecular Cell · 2013 · 305 citations · Full text

, , +13

1–5 of 33

Authors

218

  1. MB
    Marcus B. Smolka

    Cornell University, United States

    5 publications · 288 citations

    5

    h-index

  2. HD
    Haley D.M. Wyatt

    University of Toronto, Canada

    4 publications · 387 citations

    4

    h-index

  3. AS
    Agata Smogorzewska

    Rockefeller University, United States

    4 publications · 932 citations

    4

    h-index

  4. PL
    Pierre-Henri L. Gaillard

    Centre National de la Recherche Scientifique, France

    4 publications · 747 citations

    4

    h-index

  5. TM
    Thomas Macartney

    MRC Protein Phosphorylation and Ubiquitylation Unit, United Kingdom

    4 publications · 557 citations

    4

    h-index

1–5 of 218

Institutions

100

  1. Cornell University

    Ithaca, United States

    6 h-index

    19 publications

    1.3K citations

  2. University of Toronto

    Toronto, Canada

    5 h-index

    30 publications

    969 citations

  3. MRC Protein Phosphorylation and Ubiquitylation Unit

    Dundee, United Kingdom

    4 h-index

    25 publications

    4K citations

  4. Aix-Marseille Université

    Marseille, France

    4 h-index

    23 publications

    4K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    31 publications

    4.6K citations

  6. University of Dundee

    Dundee, United Kingdom

    4 h-index

    30 publications

    5.1K citations

  7. Centre de Recherche en Cancérologie de Marseille

    Marseille, France

    3 h-index

    20 publications

    2.8K citations

  8. Shanghai Institutes for Biological Sciences

    Shanghai, China

    2 h-index

    8 publications

    540 citations

1–8 of 100

Venues

  1. Molecular Cell

    5 publications · 977 citations

    5

    h-index

  2. Nucleic Acids Research

    4 publications · 123 citations

    4

    h-index

  3. Cell Reports

    4 publications · 212 citations

    4

    h-index

  4. The EMBO Journal

    2 publications · 83 citations

    2

    h-index

  5. The Journal of Cell Biology

    JCB · 2 publications · 165 citations

    2

    h-index

1–5