Identification of the breast cancer susceptibility gene BRCA2

Richard Wooster, Graham R. Bignell, Jonathan Lancaster, +37

Nature

Breast OncologyCancer GenomicsBreast CancerCancer GeneticsMedicine +1

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

Sonam Dolma, Stephen L. Lessnick, William C. Hahn, +1

Cancer Cell

Tumor BiologyOncogenic AgentMedicinePharmacologyGenotype-selective Antitumor Agents +7

Interaction of the Fanconi Anemia Proteins and BRCA1 in a Common Pathway

Irene García-Higuera, Toshiyasu Taniguchi, Shridar Ganesan, +5

Molecular Cell

Signal TransductionGeneticsCommon PathwayHeme SignalingMolecular Genetics +5

Biallelic Inactivation of <i>BRCA2</i> in Fanconi Anemia

Niall G. Howlett, Toshiyasu Taniguchi, Susan B. Olson, +10

Science

Biallelic InactivationGenome InstabilityFanconi AnemiaSomatic VariantGenetics +10

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

Nazneen Rahman, Sheila Seal, Deborah J. Thompson, +14

Nature Genetics

Tumor BiologyBreast OncologyBrca2-interacting ProteinMedicineNatural Sciences +9

A 20-year perspective on the International Fanconi Anemia Registry (IFAR)

David I. Kutler, Bhuvanesh Singh, Jaya M. Satagopan, +5

Blood

GeneticsPathologyAplastic AnemiaAnemiaFanconi Anemia +17

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

Sheila Seal, Deborah J. Thompson, Anthony Renwick, +14

Nature Genetics

Allelic VariantSomatic VariantMedicineGeneticsPathology +5

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

Alfons Meindl, Heide Hellebrand, Constanze Wiek, +21

Nature Genetics

Breast OncologySomatic VariantCancer PathologyOvarian Cancer PedigreesGenetics +7

Identification of the FANCI Protein, a Monoubiquitinated FANCD2 Paralog Required for DNA Repair

Agata Smogorzewska, Shuhei Matsuoka, Patrizia Vinciguerra, +8

Cell

ChromatinGenome InstabilityFanci ProteinDna SequencingGenetics +3

RAP80 Targets BRCA1 to Specific Ubiquitin Structures at DNA Damage Sites

Bijan Sobhian, Genze Shao, Dana R. Lilli, +5

Science