Concepedia

Single-nucleotide Variant Correction

Single-Nucleotide Variant Correction is a genome editing technique that precisely modifies individual nucleotides in DNA to correct pathogenic point mutations without inducing double-strand breaks, thereby enabling the targeted restoration of normal gene function.

9

Publications

674

Citations

80

Authors

38

Institutions

Publications per year

2017–2026

3

Parents

Publications

9

Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide.

Kyung Chul Yoon, Allyson Cole-Strauss, Eric B. Kmiec · Proceedings of the National Academy of Sciences · 1996 · 220 citations · Full text

, , +13

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants

Francisco J. Sánchez‐Rivera, Bianca J. Diaz, Edward R. Kastenhuber et al. · Nature Biotechnology · 2022 · 129 citations · Full text

, , +14

Deamination Effects in Formalin-Fixed, Paraffin-Embedded Tissue Samples in the Era of Precision Medicine

Seokhwi Kim, Charny Park, Yongick Ji et al. · Journal of Molecular Diagnostics · 2016 · 73 citations · Full text

, , +17

Shimmer: detection of genetic alterations in tumors using next-generation sequence data

Nancy F. Hansen, Jared J. Gartner, Mei Lan et al. · Bioinformatics · 2013 · 68 citations · Full text

, , +17

TALEN-mediated single-base-pair editing identification of an intergenic mutation upstream of <i>BUB1B</i> as causative of PCS (MVA) syndrome

Hiroshi Ochiai, Tatsuo Miyamoto, Akinori Kanai et al. · Proceedings of the National Academy of Sciences · 2013 · 64 citations · Full text

, , +15

1–5 of 9

Authors

80

  1. FJ
    Francisco J. Sánchez‐Rivera

    Memorial Sloan Kettering Cancer Center, United States

    1 publications · 129 citations

    1

    h-index

  2. SK
    Seokhwi Kim

    Samsung Medical Center, South Korea

    1 publications · 73 citations

    1

    h-index

  3. HS
    Henri Schmidt

    Princeton University, United States

    1 publications · 129 citations

    1

    h-index

  4. TK
    Tadashi Kajii

    Yamaguchi University, Japan

    1 publications · 64 citations

    1

    h-index

  5. DC
    Debyani Chakravarty

    Memorial Sloan Kettering Cancer Center, United States

    1 publications · 129 citations

    1

    h-index

1–5 of 80

Institutions

38

  1. National Human Genome Research Institute

    Bethesda, United States

    1 h-index

    5 publications

    340 citations

  2. National Institute of Technology, Tokyo College

    Hachiōji, Japan

    1 h-index

    1 publications

    64 citations

  3. Shanghai Medical College of Fudan University

    Shanghai, China

    1 h-index

    1 publications

    55 citations

  4. Memorial Sloan Kettering Cancer Center

    New York, United States

    1 h-index

    16 publications

    2.1K citations

  5. Tianjin Normal University

    Tianjin, China

    1 h-index

    1 publications

    55 citations

  6. Stanford Medicine

    Stanford, United States

    1 h-index

    1 publications

    21 citations

  7. Intelligent Synthetic Biology Center

    Daejeon, South Korea

    1 h-index

    2 publications

    110 citations

  8. National Cancer Center

    Goyang-si, South Korea

    1 h-index

    1 publications

    73 citations

1–8 of 38

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 284 citations

    2

    h-index

  2. Blood

    1 publications · 21 citations

    1

    h-index

  3. Journal of Molecular Diagnostics

    JMD · 1 publications · 73 citations

    1

    h-index

  4. PLoS ONE

    1 publications · 32 citations

    1

    h-index

  5. Cold Spring Harbor Protocols

    1 publications · 12 citations

    1

    h-index

1–5