Concepedia

Sequence Constraints

Sequence Constraints is a genetic principle that restricts nucleotide substitutions in overlapping gene regions due to the requirement to preserve functional coding sequences in multiple reading frames simultaneously.

190

Publications

18.1K

Citations

799

Authors

370

Institutions

Publications per year

2017–2026

54

Variants

Sequence Constraint

Parents

Publications

190

RNA editing with CRISPR-Cas13

David Cox, Jonathan S. Gootenberg, Omar O. Abudayyeh et al. · Science · 2017 · 1.8K citations · Full text

, , +17

Distribution and intensity of constraint in mammalian genomic sequence

Gregory M. Cooper, Eric A. Stone, George Asimenos et al. · Genome Research · 2005 · 1.4K citations · Full text

, , +15

PROMALS3D: a tool for multiple protein sequence and structure alignments

Jimin Pei, Bong-Hyun Kim, Nick V. Grishin · Nucleic Acids Research · 2008 · 1.4K citations · Full text

, , +15

A high-resolution map of human evolutionary constraint using 29 mammals

Kerstin Lindblad‐Toh, Manuel Garber, Or Zuk et al. · Nature · 2011 · 1.2K citations · Full text

, , +17

The minimum information about a genome sequence (MIGS) specification

Dawn Field, George M Garrity, Tanya Gray et al. · Nature Biotechnology · 2008 · 1.2K citations

, , +11

1–5 of 190

Authors

799

  1. RB
    Rolf Backofen

    University of Freiburg, Germany

    5 publications · 167 citations

    5

    h-index

  2. KC
    Kui Cai

    Singapore University of Technology and Design, Singapore

    5 publications · 180 citations

    5

    h-index

  3. KA
    Kees A. Schouhamer Immink

    Singapore University of Technology and Design, Singapore

    4 publications · 162 citations

    4

    h-index

  4. RG
    Ryan Gabrys

    Technion – Israel Institute of Technology, Israel

    3 publications · 107 citations

    3

    h-index

  5. MM
    M. Mar Albà

    Universitat Pompeu Fabra, Spain

    3 publications · 645 citations

    3

    h-index

1–5 of 799

Institutions

370

  1. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    24 publications

    1.1K citations

  2. Harvard University

    Cambridge, United States

    6 h-index

    13 publications

    4.4K citations

  3. National Institutes of Health

    Bethesda, United States

    6 h-index

    12 publications

    6.9K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    10 publications

    1.5K citations

  5. Universitat Pompeu Fabra

    Barcelona, Spain

    5 h-index

    12 publications

    2.4K citations

  6. Scripps Research Institute

    San Diego, United States

    5 h-index

    12 publications

    371 citations

  7. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    34 publications

    38.6K citations

  8. University of Colorado Boulder

    Boulder, United States

    5 h-index

    7 publications

    2.4K citations

1–8 of 370

Venues

  1. Journal of Molecular Evolution

    7 publications · 247 citations

    7

    h-index

  2. Nucleic Acids Research

    7 publications · 1.7K citations

    7

    h-index

  3. International Journal of Production Research

    7 publications · 324 citations

    7

    h-index

  4. Molecular Biology and Evolution

    MBE · 6 publications · 301 citations

    6

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 617 citations

    6

    h-index

1–5