Gregory M. Cooper

A general framework for estimating the relative pathogenicity of human genetic variants

Martin Kircher, Daniela Witten, Preti Jain et al. · Nature Genetics · 2014 · 6.6K citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

CADD: predicting the deleteriousness of variants throughout the human genome

Philipp Rentzsch, Daniela Witten, Gregory M. Cooper et al. · Nucleic Acids Research · 2018 · 3.9K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

Richard A. Gibbs, George M. Weinstock, Michael L. Metzker et al. · Nature · 2004 · 2.2K citations · Full text

Life Sciences, Evolutionary Biology, Genetics +17

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

Eugene Davydov, David L. Goode, Marina Sirota et al. · PLoS Computational Biology · 2010 · 1.9K citations · Full text

Life Sciences, Bioinformatics, Biology +17

Rare Structural Variants Disrupt Multiple Genes in Neurodevelopmental Pathways in Schizophrenia

Tom Walsh, Jon McClellan, Shane McCarthy et al. · Science · 2008 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +17