Concepedia

Scramblase Activation

Scramblase Activation is a biochemical regulatory process characterized by the induction of scramblase enzyme activity, which disrupts phospholipid asymmetry across the plasma membrane by facilitating the calcium-dependent, bidirectional translocation of phosphatidylserine from the inner to the outer leaflet.

76

Publications

6.1K

Citations

332

Authors

114

Institutions

Publications per year

2017–2026

29

Parents

Publications

76

Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes.

Bret Verhoven, Robert Schlegel, Paula Williamson · The Journal of Experimental Medicine · 1995 · 661 citations · Full text

, , +17

X-ray structure of a calcium-activated TMEM16 lipid scramblase

Janine D. Brunner, Novandy K. Lim, Stephan Schenck et al. · Nature · 2014 · 477 citations

, , +14

Calcium-dependent Phospholipid Scramblase Activity of TMEM16 Protein Family Members

Jun Suzuki, Toshihiro Fujii, Takeshi Imao et al. · Journal of Biological Chemistry · 2013 · 383 citations · Full text

, , +17

Role of Ca<sup>2+</sup>-activated K<sup>+</sup> channels in human erythrocyte apoptosis

Philipp A. Lang, Stefanie Kaiser, Swetlana Myssina et al. · American Journal of Physiology-Cell Physiology · 2003 · 382 citations

, , +17

Regulation of Phospholipid Scramblase Activity during Apoptosis and Cell Activation by Protein Kinase Cδ

S. Courtney Frasch, Peter M. Henson, Jenai M. Kailey et al. · Journal of Biological Chemistry · 2000 · 238 citations · Full text

, , +15

1–5 of 76

Authors

332

  1. PJ
    Peter J. Sims

    Oklahoma Medical Research Foundation, United States

    7 publications · 552 citations

    7

    h-index

  2. PC
    Paul Comfurius

    Maastricht University, Netherlands

    6 publications · 401 citations

    6

    h-index

  3. TW
    Therese Wiedmer

    Oklahoma Medical Research Foundation, United States

    6 publications · 498 citations

    6

    h-index

  4. EM
    Edouard M. Bevers

    Maastricht University, Netherlands

    6 publications · 401 citations

    6

    h-index

  5. RZ
    R.F.A. Zwaal

    Maastricht University, Netherlands

    6 publications · 401 citations

    6

    h-index

1–5 of 332

Institutions

114

  1. Cornell University

    Ithaca, United States

    7 h-index

    30 publications

    2.3K citations

  2. University of Tübingen

    Tübingen, Germany

    5 h-index

    47 publications

    7.9K citations

  3. The University of Osaka

    Osaka, Japan

    4 h-index

    14 publications

    616 citations

  4. Versiti Blood Center of Wisconsin

    Milwaukee, United States

    4 h-index

    15 publications

    927 citations

  5. Scripps Research Institute

    San Diego, United States

    4 h-index

    17 publications

    1.7K citations

  6. University of Zurich

    Zurich, Switzerland

    4 h-index

    15 publications

    3.1K citations

  7. Maastricht University

    Maastricht, The Netherlands

    4 h-index

    24 publications

    1.5K citations

  8. Vietnam National University of Agriculture

    Hanoi, Vietnam

    3 h-index

    3 publications

    250 citations

1–8 of 114

Venues

  1. Biochemistry

    8 publications · 480 citations

    8

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  2. Journal of Biological Chemistry

    JBC · 8 publications · 978 citations

    8

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  3. Nature Communications

    6 publications · 464 citations

    6

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  4. Cellular Physiology and Biochemistry

    4 publications · 265 citations

    4

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  5. Blood

    3 publications · 204 citations

    3

    h-index

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