Concepedia

Phosphatidylserine Externalization

Phosphatidylserine Externalization is a regulated plasma membrane phospholipid translocation process in which phosphatidylserine is redistributed from the inner to the outer leaflet of the cell membrane, typically during apoptosis, thereby exposing an “eat-me” signal that promotes recognition and clearance of dying cells.

411

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30.5K

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1.8K

Authors

553

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2017–2026

57

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Publications

411

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

Séamus J. Martin, Chris Reutelingsperger, Anne J. McGahon et al. · The Journal of Experimental Medicine · 1995 · 2.9K citations · Full text

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Membrane and Morphological Changes in Apoptotic Cells Regulated by Caspase-Mediated Activation of PAK2

Thomas Rudel, Gary Bokoch · Science · 1997 · 748 citations

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Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes.

Bret Verhoven, Robert Schlegel, Paula Williamson · The Journal of Experimental Medicine · 1995 · 661 citations · Full text

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Loss of Phospholipid Asymmetry and Surface Exposure of Phosphatidylserine Is Required for Phagocytosis of Apoptotic Cells by Macrophages and Fibroblasts

Valerie A. Fadok, Aimee de Cathelineau, David L. Daleke et al. · Journal of Biological Chemistry · 2001 · 637 citations · Full text

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An essential role for a phospholipid transfer protein in yeast Golgi function

Vytas A. Bankaitis, Jacqueline R. Aitken, Ann E. Cleves et al. · Nature · 1990 · 549 citations

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1–5 of 411

Authors

1.8K

  1. FL
    Florian Läng

    University of Tübingen, Germany

    31 publications · 1.6K citations

    26

    h-index

  2. VE
    Valerian E. Kagan

    University of Pittsburgh, United States

    16 publications · 1.1K citations

    14

    h-index

  3. YY
    Yulia Y. Tyurina

    University of Pittsburgh, United States

    10 publications · 793 citations

    10

    h-index

  4. VA
    Vladimir A. Tyurin

    University of Pittsburgh, United States

    9 publications · 855 citations

    9

    h-index

  5. AJ
    Alan J. Schroit

    The University of Texas MD Anderson Cancer Center, United States

    9 publications · 555 citations

    9

    h-index

1–5 of 1.8K

Institutions

553

  1. University of Tübingen

    Tübingen, Germany

    27 h-index

    162 publications

    9.4K citations

  2. Inserm

    Paris, France

    19 h-index

    85 publications

    3.8K citations

  3. University of Pittsburgh

    Pittsburgh, United States

    14 h-index

    85 publications

    6.3K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    11 h-index

    38 publications

    3.1K citations

  5. Harvard University

    Cambridge, United States

    10 h-index

    15 publications

    689 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    30 publications

    1.1K citations

  7. Karolinska Institutet

    Stockholm, Sweden

    8 h-index

    23 publications

    2.1K citations

  8. Institut de Virologie

    Strasbourg, France

    8 h-index

    17 publications

    708 citations

1–8 of 553

Venues

  1. Journal of Biological Chemistry

    JBC · 25 publications · 3.3K citations

    25

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  2. Cellular Physiology and Biochemistry

    22 publications · 1.3K citations

    21

    h-index

  3. 16

    h-index

  4. Blood

    13 publications · 1.3K citations

    12

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 12 publications · 498 citations

    11

    h-index

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