Robert Schlegel

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.3K citations

Tumor Biology, Predictive Modelling, Drug Target +12

Next-generation characterization of the Cancer Cell Line Encyclopedia

Mahmoud Ghandi, Franklin W. Huang, Judit Jané‐Valbuena et al. · Nature · 2019 · 3.5K citations · Full text

Tumor Heterogeneity, Medicine, Cancer Genomics +6

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

Cory M. Johannessen, Jesse S. Boehm, So Young Kim et al. · Nature · 2010 · 1.4K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Pathway +9

Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis.

J Tsai, Mark A. Perrella, M Yoshizumi et al. · Proceedings of the National Academy of Sciences · 1994 · 803 citations · Full text

Inflammation, Vascular Disease, Cardiovascular Disease +12

Activation of MET via Diverse Exon 14 Splicing Alterations Occurs in Multiple Tumor Types and Confers Clinical Sensitivity to MET Inhibitors

Garrett M. Frampton, Siraj M. Ali, Mark R. Rosenzweig et al. · Cancer Discovery · 2015 · 782 citations · Full text