Concepedia

Replication Origin Firing Rate

Replication Origin Firing Rate is a quantitative metric in molecular biology that denotes the frequency per unit time at which a specific genomic locus initiates DNA replication during the S phase of the cell cycle, distinguishing it from other replication-related metrics by its focus on temporal activation kinetics of individual origins.

26

Publications

1.7K

Citations

84

Authors

56

Institutions

Publications per year

2017–2026

2

Parents

Publications

26

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

Seiji Tanaka, Ryuichiro Nakato, Yuki Katou et al. · Current Biology · 2011 · 261 citations · Full text

, , +9

The replication rate of human hematopoietic stem cells in vivo

Sandra N. Catlin, Lambert Busque, Rosemary E. Gale et al. · Blood · 2011 · 252 citations · Full text

, , +5

Evidence for Sequential and Increasing Activation of Replication Origins along Replication Timing Gradients in the Human Genome

Guillaume Guilbaud, Aurélien Rappailles, Antoine Baker et al. · PLoS Computational Biology · 2011 · 146 citations · Full text

, , +15

DNA replication timing: random thoughts about origin firing

Nature Cell Biology · 2006 · 126 citations · Full text

, , +15

Stochastic hybrid modeling of DNA replication across a complete genome

John Lygeros, Konstantinos Koutroumpas, Sotiris Dimopoulos et al. · Proceedings of the National Academy of Sciences · 2008 · 91 citations · Full text

, , +16

1–5 of 26

Authors

84

  1. JB
    John Bechhoefer

    Simon Fraser University, Canada

    7 publications · 259 citations

    7

    h-index

  2. OH
    Olivier Hyrien

    Centre National de la Recherche Scientifique, France

    4 publications · 272 citations

    4

    h-index

  3. AG
    Arach Goldar

    Commissariat à l'Énergie Atomique et aux Énergies Alternatives, France

    4 publications · 272 citations

    4

    h-index

  4. AB
    Antoine Baker

    Centre National de la Recherche Scientifique, France

    3 publications · 197 citations

    3

    h-index

  5. AA
    A. Arnéodo

    Centre National de la Recherche Scientifique, France

    3 publications · 207 citations

    3

    h-index

1–5 of 84

Institutions

56

  1. Simon Fraser University

    Burnaby, Canada

    7 h-index

    15 publications

    540 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    27 publications

    2.2K citations

  3. Inserm

    Paris, France

    4 h-index

    13 publications

    955 citations

  4. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    4 h-index

    7 publications

    395 citations

  5. Université Claude Bernard Lyon 1

    Villeurbanne, France

    3 h-index

    8 publications

    593 citations

  6. École Normale Supérieure de Lyon

    Lyon, France

    3 h-index

    8 publications

    593 citations

  7. Institut de Biologie de l'École Normale Supérieure

    Paris, France

    3 h-index

    7 publications

    541 citations

  8. Rockefeller University

    New York, United States

    2 h-index

    4 publications

    288 citations

1–8 of 56

Venues

  1. Physical Review E

    PRE · 2 publications · 39 citations

    2

    h-index

  2. Physical Review Letters

    PRL · 2 publications · 55 citations

    2

    h-index

  3. PLoS Computational Biology

    2 publications · 190 citations

    2

    h-index

  4. Genome Research

    GR · 2 publications · 101 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 101 citations

    2

    h-index

1–5