Concepedia

Replication Initiation Checkpoints

Replication Initiation Checkpoints is a regulatory mechanism in cell cycle control that ensures the precise timing and fidelity of DNA replication by preventing the activation of replication origins until the necessary conditions for initiation are met.

161

Publications

13.8K

Citations

640

Authors

233

Institutions

Publications per year

2017–2026

21

Parents

Publications

161

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

Piers Nash, Xiaojing Tang, Stephen Orlicky et al. · Nature · 2001 · 759 citations

, , +13

A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication

Corrado Santocanale, John F.X. Diffley · Nature · 1998 · 646 citations

, , +14

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

A Letessier, Gaël A. Millot, Stéphane Koundrioukoff et al. · Nature · 2011 · 419 citations

, , +14

Hydroxyurea Arrests DNA Replication by a Mechanism That Preserves Basal dNTP Pools

Ahmet Koç, Linda J. Wheeler, Christopher K. Mathews et al. · Journal of Biological Chemistry · 2003 · 415 citations · Full text

, , +14

Regulation of DNA-replication origins during cell-cycle progression

Katsuhiko Shirahige, Yuji Hori, Katsuya Shiraishi et al. · Nature · 1998 · 413 citations

, , +14

1–5 of 161

Authors

640

  1. HM
    Hisao Masai

    Tokyo Metropolitan Institute of Medical Science, Japan

    6 publications · 269 citations

    6

    h-index

  2. PN
    Paul Nurse

    The Honourable Society of Lincoln's Inn, United Kingdom

    6 publications · 464 citations

    6

    h-index

  3. JF
    John F.X. Diffley

    The Francis Crick Institute, United Kingdom

    5 publications · 1.4K citations

    5

    h-index

  4. CS
    Corrado Santocanale

    Ollscoil na Gaillimhe – University of Galway, Ireland

    4 publications · 1K citations

    4

    h-index

  5. JJ
    J. Julian Blow

    University of Dundee, United Kingdom

    4 publications · 514 citations

    4

    h-index

1–5 of 640

Institutions

233

  1. Centre National de la Recherche Scientifique

    Paris, France

    11 h-index

    48 publications

    6.4K citations

  2. Cancer Research UK

    London, United Kingdom

    8 h-index

    22 publications

    2.1K citations

  3. Roswell Park Comprehensive Cancer Center

    Buffalo, United States

    7 h-index

    24 publications

    1.9K citations

  4. Wellcome Trust

    London, United Kingdom

    7 h-index

    24 publications

    1.8K citations

  5. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    6 h-index

    22 publications

    2.9K citations

  6. Stanford University

    Stanford, United States

    6 h-index

    15 publications

    1.3K citations

  7. Cancer Genetics (United States)

    Rutherford, United States

    6 h-index

    21 publications

    1.5K citations

  8. Tokyo Metropolitan Institute of Medical Science

    Tokyo, Japan

    6 h-index

    28 publications

    1.3K citations

1–8 of 233

Venues

  1. The EMBO Journal

    13 publications · 1.1K citations

    12

    h-index

  2. Genes & Development

    8 publications · 1K citations

    8

    h-index

  3. Cell

    7 publications · 797 citations

    7

    h-index

  4. Journal of Biological Chemistry

    JBC · 7 publications · 752 citations

    7

    h-index

  5. Molecular Cell

    7 publications · 873 citations

    7

    h-index

1–5