Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

A Letessier, Gaël A. Millot, Stéphane Koundrioukoff, +6

Nature

Genome InstabilityNatural SciencesFra3b Fragile SiteDna ReplicationMolecular Biology +4

Comprehensive Profiling of 8p11-12 Amplification in Breast Cancer

Véronique Gelsi‐Boyer, Béatrice Orsetti, Nathalie Cervera, +19

Molecular Cancer Research

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers

A Letessier, Fabrice Sircoulomb, Christophe Ginestier, +12

BMC Cancer

Stepwise Activation of the ATR Signaling Pathway upon Increasing Replication Stress Impacts Fragile Site Integrity

Stéphane Koundrioukoff, Sandra Carignon, Hervé Técher, +3

PLoS Genetics

Fork ProtectionGenomic MechanismMolecular BiologyCell CycleEpigenetics +14

Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

Nausica Arnoult, Caroline Schluth‐Bolard, A Letessier, +9

PLoS Genetics

Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer

A Letessier, Sarah Garrido‐Urbani, Christophe Ginestier, +12

Oncogene

Cancer ResearchBreast OncologyPoor OutcomeMedicineCell Death +8

ERBB2 phosphorylation and trastuzumab sensitivity of breast cancer cell lines

Christophe Ginestier, J Adélaïde, A Gonçalvès, +10

Oncogene

Erbb2 PhosphorylationBreast OncologySignal TransductionMedicineReceptor Tyrosine Kinase +6

Candidate Luminal B Breast Cancer Genes Identified by Genome, Gene Expression and DNA Methylation Profiling

Stéphanie Cornen, Arnaud Guillé, José Adélaı̈de, +15

PLoS ONE

Breast OncologyOncologyMedicineGeneticsDna Methylation +13

A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/<i>NRG1</i> gene

José Adélaı̈de, Huai-En Huang, Anne Murati, +12

Genes Chromosomes and Cancer

<i>ETV6</i> gene rearrangements in invasive breast carcinoma

A Letessier, Christophe Ginestier, Emmanuelle Charafe‐Jauffret, +8

Genes Chromosomes and Cancer

Etv6/tel GeneBac ProbesMedicineGeneticsGene Expression +10