Stephen Orlicky

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

Piers Nash, Xiaojing Tang, Stephen Orlicky et al. · Nature · 2001 · 754 citations

Genome Instability, Signal Transduction, Cell Regulation +10

Structural Basis for Phosphodependent Substrate Selection and Orientation by the SCFCdc4 Ubiquitin Ligase

Stephen Orlicky, Xiaojing Tang, Andrew Willems et al. · Cell · 2003 · 503 citations

Phosphodependent Substrate Selection, Biochemistry, Structural Bioinformatics +7

Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor

Tanja Mittag, Stephen Orlicky, Wing‐Yiu Choy et al. · Proceedings of the National Academy of Sciences · 2008 · 342 citations · Full text

Protein Assembly, Molecular Biology, Single Molecule Biophysics +20

Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 with the Cdc4 Subunit of an SCF Ubiquitin Ligase

Tanja Mittag, Joseph A. Marsh, Alexander Grishaev et al. · Structure · 2010 · 273 citations · Full text

Dynamic Complex, Protein Folding, Molecular Biology +5

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Derek F. Ceccarelli, Xiaojing Tang, Benoit Pelletier et al. · Cell · 2011 · 230 citations · Full text

Medicine, Allosteric Inhibitor, Drug Development +2