Concepedia

Replication Fork Reversal

Replication Fork Reversal is a DNA damage response mechanism in which a stalled replication fork undergoes structural reorganization into a four-way junction resembling a Holliday structure, allowing for error-free lesion bypass, fork stabilization, and the prevention of genomic instability.

102

Publications

10.8K

Citations

497

Authors

188

Institutions

Publications per year

2017–2026

50

Variants

Fork Regression

Parents

Publications

102

Fork Reversal and ssDNA Accumulation at Stalled Replication Forks Owing to Checkpoint Defects

José M. Sogo, Massimo Lopes, Marco Foiani · Science · 2002 · 821 citations

, , +17

Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells

Ralph Zellweger, Damian Dalcher, Karun Mutreja et al. · The Journal of Cell Biology · 2015 · 689 citations · Full text

, , +17

Topoisomerase I poisoning results in PARP-mediated replication fork reversal

Arnab Ray Chaudhuri, Yoshitami Hashimoto, Raquel Herrador et al. · Nature Structural & Molecular Biology · 2012 · 495 citations

, , +12

MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells

Delphine Lemaçon, Jessica Jackson, Annabel Quinet et al. · Nature Communications · 2017 · 417 citations · Full text

, , +16

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

Arun Mouli Kolinjivadi, Vincenzo Sannino, Anna De Antoni et al. · Molecular Cell · 2017 · 377 citations · Full text

, , +17

1–5 of 102

Authors

497

  1. ML
    Massimo Lopes

    University of Zurich, Switzerland

    19 publications · 4.6K citations

    19

    h-index

  2. BM
    Bénédicte Michel

    Département Génétique Animale, France

    11 publications · 635 citations

    11

    h-index

  3. RH
    Raquel Herrador

    University of Zurich, Switzerland

    7 publications · 2K citations

    7

    h-index

  4. RZ
    Ralph Zellweger

    University of Zurich, Switzerland

    7 publications · 2.1K citations

    7

    h-index

  5. MB
    Matteo Berti

    University of Zurich, Switzerland

    6 publications · 1.7K citations

    6

    h-index

1–5 of 497

Institutions

188

  1. University of Zurich

    Zurich, Switzerland

    18 h-index

    108 publications

    21.3K citations

  2. IFOM

    Milan, Italy

    10 h-index

    44 publications

    7.7K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    28 publications

    2.1K citations

  4. Vanderbilt University

    Nashville, United States

    9 h-index

    32 publications

    2.5K citations

  5. University of Milan

    Milan, Italy

    7 h-index

    25 publications

    4.5K citations

  6. Département Génétique Animale

    Castanet-Tolosan, France

    7 h-index

    24 publications

    1.5K citations

  7. Washington University in St. Louis

    St Louis, United States

    6 h-index

    22 publications

    5.1K citations

  8. Saint Louis University

    St Louis, United States

    6 h-index

    31 publications

    6.6K citations

1–8 of 188

Venues

  1. Molecular Cell

    13 publications · 2.3K citations

    13

    h-index

  2. Nucleic Acids Research

    11 publications · 420 citations

    11

    h-index

  3. Nature Communications

    9 publications · 1.4K citations

    9

    h-index

  4. Cell Reports

    7 publications · 502 citations

    7

    h-index

  5. Molecular Microbiology

    7 publications · 374 citations

    7

    h-index

1–5