Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers

Angelo Taglialatela, Silvia Álvarez, Giuseppe Leuzzi, +10

Molecular Cell

ChromatinGenome InstabilitySnf2-family Fork RemodelersCell RegulationMedicine +7

Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments

Arun Mouli Kolinjivadi, Vincenzo Sannino, Anna De Antoni, +9

Molecular Cell

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

Angelo Taglialatela, Giuseppe Leuzzi, Vincenzo Sannino, +6

Molecular Cell

Genome InstabilityMolecular BiologyCancer Cell BiologyPrimpol-dependent Ssdna GapsMutagenic Repair +5

Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

Antoine Aze, Vincenzo Sannino, Paolo Soffientini, +2

Nature Cell Biology

ChromatinGenome InstabilityNatural SciencesGeneticsDna Analysis +8

Structure of human Cdc45 and implications for CMG helicase function

Aline C. Simon, Vincenzo Sannino, Vincenzo Costanzo, +1

Nature Communications

POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps

Anjali Mann, Miguel Angel Ramírez-Otero, Anna De Antoni, +8

Molecular Cell

Genome InstabilityNatural SciencesGeneticsForks RuptureDna Replication +9

Increased Cerebrospinal Fluid Levels of 3,3′,5′-Triiodothyronine in Patients with Alzheimer’s Disease

Simone Sampaolo, Ángel Campos‐Barros, Gherardo Mazziotti, +5

The Journal of Clinical Endocrinology & Metabolism

Cerebrospinal Fluid LevelsNeurochemical BiomarkersAlzheimer ’Social SciencesAlzheimer's Disease +14

Fanconi-Anemia-Associated Mutations Destabilize RAD51 Filaments and Impair Replication Fork Protection

Karina Zadorozhny, Vincenzo Sannino, Ondrej Beláň, +4

Cell Reports

Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases

I. Krastanova, Vincenzo Sannino, Heinz Amenitsch, +3

Journal of Biological Chemistry

RAD51 protects abasic sites to prevent replication fork breakage

Yodhara Wijesekara Hanthi, Miguel Angel Ramírez-Otero, Robert E Appleby, +9

Molecular Cell

ChromatinGenome InstabilityBase Excision RepairChromatin RemodelingReplication Fork Breakage +9