Concepedia

Receptor Efficacy

Receptor Efficacy is the intrinsic ability of a ligand-bound receptor to activate downstream signaling pathways, distinguished from related concepts by its quantification of the maximum functional response elicited relative to a reference agonist within a given receptor system.

38

Publications

2.6K

Citations

168

Authors

62

Institutions

Publications per year

2017–2026

5

Parents

Publications

38

The selectivity of β‐adrenoceptor agonists at human β<sub>1</sub>‐, β<sub>2</sub>‐ and β<sub>3</sub>‐adrenoceptors

Jillian G. Baker · British Journal of Pharmacology · 2010 · 586 citations · Full text

, , +16

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

Alec J. Walker, Robbie G. Majzner, Ling Zhang et al. · Molecular Therapy · 2017 · 384 citations · Full text

, , +17

Bitter Taste Receptors Influence Glucose Homeostasis

Cedrick D. Dotson, Lan Zhang, Hong Xu et al. · PLoS ONE · 2008 · 283 citations · Full text

, , +17

Δ<sup>9</sup>-Tetrahydrocannabinol selectively acts on CB<sub>1</sub> receptors in specific regions of dorsal vagal complex to inhibit emesis in ferrets

Marja D. Van Sickle, Lorraine D. Oland, Ken Mackie et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2003 · 139 citations

, , +14

Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.

Finn Olav Levy, Xiaolong Zhu, Alberto J. Kaumann et al. · Proceedings of the National Academy of Sciences · 1993 · 103 citations

, , +16

1–5 of 38

Authors

168

  1. TK
    Terry Kenakin

    Research Triangle Park Foundation, United States

    3 publications · 77 citations

    3

    h-index

  2. FJ
    Frederick J. Ehlert

    University of California, Irvine, United States

    2 publications · 70 citations

    2

    h-index

  3. PC
    Peter Curzon

    Abbott Fund, United States

    2 publications · 73 citations

    2

    h-index

  4. PH
    Piet Hein Van der Graaf

    Centre for Human Drug Research, Netherlands

    2 publications · 35 citations

    2

    h-index

  5. TI
    Tom Issaevitch

    Wolfram Research (United States), United States

    1 publications · 33 citations

    1

    h-index

1–5 of 168

Institutions

62

  1. Research Triangle Park Foundation

    Durham, United States

    2 h-index

    2 publications

    37 citations

  2. Abbott (United Kingdom)

    Maidenhead, United Kingdom

    2 h-index

    13 publications

    216 citations

  3. Abbott Fund

    Chicago, United States

    2 h-index

    23 publications

    769 citations

  4. University of California, Irvine

    Irvine, United States

    2 h-index

    4 publications

    152 citations

  5. Max Planck Institute for Human Development

    Berlin, Germany

    2 h-index

    6 publications

    84 citations

  6. Centre for Human Drug Research

    Leiden, The Netherlands

    2 h-index

    2 publications

    35 citations

  7. Technische Universität Dresden

    Dresden, Germany

    1 h-index

    2 publications

    30 citations

  8. Massachusetts General Hospital

    Boston, United States

    1 h-index

    9 publications

    117 citations

1–8 of 62

Venues

  1. 4

    h-index

  2. 3

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 221 citations

    3

    h-index

  4. European Journal of Pharmacology

    EJP · 2 publications · 51 citations

    2

    h-index

  5. PLoS ONE

    2 publications · 301 citations

    2

    h-index

1–5