Alec J. Walker

Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

Timothy R. Hammond, Connor Dufort, Lasse Dissing‐Olesen et al. · Immunity · 2018 · 2.2K citations · Full text

Inflammation, Neurodegenerative Diseases, Mouse Lifespan +12

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Adrienne H. Long, Waleed Haso, Jack F. Shern et al. · Nature Medicine · 2015 · 1.7K citations · Full text

Autoimmune Disease, Tonic Signaling, Immunology +12

CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development

Emily K. Lehrman, Daniel K. Wilton, Elizabeth Y. Litvina et al. · Neuron · 2018 · 447 citations · Full text

Synaptic Plasticity, Medicine, Immunology +5

Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain

Samuel E. Marsh, Alec J. Walker, Tushar Kamath et al. · Nature Neuroscience · 2022 · 409 citations · Full text

Neurodegenerative Diseases, Glial Signatures, Neuroanatomy +12

Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase

Alec J. Walker, Robbie G. Majzner, Ling Zhang et al. · Molecular Therapy · 2017 · 372 citations · Full text