Concepedia

Ras Dimerization

RAS Dimerization is a molecular interaction mechanism within the broader class of protein oligomerization events, distinguished by the specific association of two RAS oncoprotein monomers that facilitates allosteric regulation and signal amplification in cellular signaling pathways.

126

Publications

12.9K

Citations

647

Authors

223

Institutions

Publications per year

2017–2026

31

Parents

Publications

126

An essential role for Rac in Ras transformation

Rongguo Qiu, Jing Chen, David H. Kirn et al. · Nature · 1995 · 885 citations

, , +7

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

Patricia H. Warne, Pablo Rodrigueza Vician, Julian Downward · Nature · 1993 · 728 citations

, , +10

Multiple ras functions can contribute to mammalian cell transformation

Michael A. White, Charles A. Nicolette, Audrey Minden et al. · Cell · 1995 · 650 citations · Full text

, , +11

BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

Zhan Yao, Neilawattie M. Torres, Anthony Tao et al. · Cancer Cell · 2015 · 546 citations

, , +17

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

Scott Powers, Tohru Kataoka, Ottavio Fasano et al. · Cell · 1984 · 473 citations

, , +12

1–5 of 126

Authors

647

  1. DB
    Daniel Broek

    University of Southern California, United States

    5 publications · 243 citations

    5

    h-index

  2. SK
    Shohei Koide

    University of Chicago, United States

    5 publications · 196 citations

    5

    h-index

  3. AP
    Andrea Parmeggiani

    École Polytechnique, France

    4 publications · 87 citations

    4

    h-index

  4. JF
    John F. Hancock

    The University of Queensland, Australia

    4 publications · 306 citations

    4

    h-index

  5. SP
    Scott Powers

    Cold Spring Harbor Laboratory, United States

    4 publications · 726 citations

    4

    h-index

1–5 of 647

Institutions

223

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    29 publications

    5.2K citations

  2. Max Planck Institute of Molecular Physiology

    Dortmund, Germany

    8 h-index

    19 publications

    1.3K citations

  3. New York University

    New York, United States

    8 h-index

    13 publications

    1K citations

  4. University of California, Berkeley

    Berkeley, United States

    7 h-index

    28 publications

    3.2K citations

  5. University of California, San Francisco

    San Francisco, United States

    7 h-index

    28 publications

    5.3K citations

  6. Frederick National Laboratory for Cancer Research

    Frederick, United States

    7 h-index

    18 publications

    1.7K citations

  7. National Cancer Institute

    Bethesda, United States

    6 h-index

    20 publications

    1.4K citations

  8. Tokyo University of Science

    Tokyo, Japan

    5 h-index

    11 publications

    473 citations

1–8 of 223

Venues

  1. Journal of Biological Chemistry

    JBC · 11 publications · 1.2K citations

    11

    h-index

  2. Nature

    7 publications · 2.6K citations

    7

    h-index

  3. PubMed

    Repository · 6 publications · 550 citations

    6

    h-index

  4. Molecular and Cellular Biology

    MCB · 6 publications · 526 citations

    6

    h-index

  5. Cell

    5 publications · 2.1K citations

    5

    h-index

1–5