Concepedia

Rad50 Atpase Function

RAD50 ATPase Function is a molecular enzymatic activity that belongs to the ATPase family of proteins and specifically mediates the hydrolysis of ATP to regulate structural dynamics and DNA end tethering during DNA double-strand break repair within the context of the MRN complex.

38

Publications

4.5K

Citations

148

Authors

43

Institutions

Publications per year

2017–2026

9

Parents

Publications

38

Structural Biology of Rad50 ATPase

Karl‐Peter Hopfner, Annette Kärcher, David Shin et al. · Cell · 2000 · 913 citations · Full text

, , +10

Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

Tanya T. Paull, Martin Gellert · Genes & Development · 1999 · 537 citations · Full text

, , +11

Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase

Karl‐Peter Hopfner, Annette Kärcher, Lisa Craig et al. · Cell · 2001 · 514 citations · Full text

, , +14

The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair

Katja Lammens, Derk Bemeleit, Carolin Möckel et al. · Cell · 2011 · 209 citations · Full text

, , +13

ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair

Gareth J. Williams, R. Scott Williams, Jessica S. Williams et al. · Nature Structural & Molecular Biology · 2011 · 162 citations · Full text

, , +10

1–5 of 38

Authors

148

  1. KH
    Karl‐Peter Hopfner

    Ludwig-Maximilians-Universität München, Germany

    10 publications · 2.2K citations

    10

    h-index

  2. KL
    Katja Lammens

    Ludwig-Maximilians-Universität München, Germany

    7 publications · 688 citations

    7

    h-index

  3. JA
    John A. Tainer

    Scripps Research Institute, United States

    5 publications · 1.8K citations

    5

    h-index

  4. TT
    Tanya T. Paull

    The University of Texas at Austin, United States

    5 publications · 932 citations

    5

    h-index

  5. SW
    Scott W. Nelson

    Iowa State University, United States

    4 publications · 118 citations

    4

    h-index

1–5 of 148

Institutions

43

  1. Ludwig-Maximilians-Universität München

    Munich, Germany

    7 h-index

    41 publications

    5K citations

  2. Center for Integrated Protein Science Munich

    Munich, Germany

    6 h-index

    10 publications

    1.3K citations

  3. Scripps Research Institute

    San Diego, United States

    5 h-index

    25 publications

    9.3K citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    6 publications

    1.6K citations

  5. The University of Texas at Austin

    Austin, United States

    4 h-index

    17 publications

    1.8K citations

  6. Iowa State University

    Ames, United States

    4 h-index

    12 publications

    343 citations

  7. Lawrence Berkeley National Laboratory

    Berkeley, United States

    3 h-index

    9 publications

    1.7K citations

  8. Tel Aviv University

    Tel Aviv, Israel

    3 h-index

    10 publications

    254 citations

1–8 of 43

Venues

  1. Nucleic Acids Research

    8 publications · 418 citations

    8

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 199 citations

    5

    h-index

  3. The EMBO Journal

    5 publications · 510 citations

    5

    h-index

  4. Nature Structural & Molecular Biology

    3 publications · 383 citations

    3

    h-index

  5. Cell

    3 publications · 1.6K citations

    3

    h-index

1–5