Dna End Resection

DNA End Resection is a DNA repair process in which the 5' ends of double-strand breaks are enzymatically degraded to generate 3' single-stranded overhangs, thereby initiating homology-directed repair pathways.

Publications

94.4K

Citations

4.3K

Authors

925

Institutions

Publications per year

2017–2026

304

Parents

Dna Repair

Children

5' To 3' Nuclease ActivityBloom Syndrome Helicase FunctionCell Cycle Control Of ResectionChromatin Remodeling At Dna EndsCtip PhosphorylationCtip-mediated Resection InitiationDna Damage Checkpoint SignalingDna End BridgingDna End ProcessingDna End Tethering

Publications

Human CtIP promotes DNA end resection

Alessandro A. Sartori, Claudia Lukas, Julia Coates et al. · Nature · 2007 · 1.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +9

(ADP-ribose)n participates in DNA excision repair

Barbara W. Durkacz, Olusesan Omidiji, Douglas A. Gray et al. · Nature · 1980 · 1.1K citations

Life Sciences, Biochemistry, Molecular Biology +9

The importance of repairing stalled replication forks

Michael M. Cox, Myron F. Goodman, Kenneth N. Kreuzer et al. · Nature · 2000 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +12

Sgs1 Helicase and Two Nucleases Dna2 and Exo1 Resect DNA Double-Strand Break Ends

Zhu Zhu, Woo-Hyun Chung, Eun Yong Shim et al. · Cell · 2008 · 1K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The 3′ to 5′ Exonuclease Activity of Mre11 Facilitates Repair of DNA Double-Strand Breaks

Tanya T. Paull, Martin Gellert · Molecular Cell · 1998 · 912 citations · Full text

Life Sciences, Genetics, Molecular Biology +15

1–5 of 1K

Authors

4.3K

PĆ
Petr Ćejka
Università della Svizzera italiana, Switzerland
28 publications · 3.1K citations
23
h-index
PS
Patrick Sung
Yale University, United States
21 publications · 1.5K citations
20
h-index
SP
Stephen P. Jackson
The Gurdon Institute, United Kingdom
18 publications · 4.2K citations
17
h-index
TT
Tanya T. Paull
The University of Texas at Austin, United States
18 publications · 2.6K citations
17
h-index
PH
Pablo Huertas
Centro Andaluz de Biología Molecular y Medicina Regenerativa, Spain
16 publications · 1.8K citations
16
h-index

1–5 of 4.3K

Institutions

925

1–8 of 925

Venues

Molecular Cell
59 publications · 10.9K citations
49
h-index
Nucleic Acids Research
125 publications · 5.3K citations
45
h-index
Journal of Biological Chemistry
JBC · 70 publications · 5.4K citations
40
h-index
Nature
41 publications · 15.1K citations
39
h-index
Nature Communications
57 publications · 3.9K citations
38
h-index

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