Concepedia

Dna End Tethering

DNA End Tethering is a molecular mechanism in double-strand break repair that functions to maintain the physical proximity of broken DNA ends, thereby preventing their separation and facilitating accurate rejoining through non-homologous end joining or homology-directed repair pathways.

29

Publications

2.3K

Citations

183

Authors

79

Institutions

Publications per year

2017–2026

11

Parents

Publications

29

Human Rad50/Mre11 Is a Flexible Complex that Can Tether DNA Ends

Martijn de Jager, John van Noort, Dik C. van Gent et al. · Molecular Cell · 2001 · 506 citations · Full text

, , +9

Oxidative Thymine Dimer Repair in the DNA Helix

Peter J. Dandliker, R. Erik Holmlin, Jacqueline K. Barton · Science · 1997 · 433 citations

, , +15

ATP‐driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling

Rajashree A. Deshpande, Gareth J. Williams, Oliver Limbo et al. · The EMBO Journal · 2014 · 144 citations · Full text

, , +16

Dna2 nuclease-helicase structure, mechanism and regulation by Rpa

Chun Zhou, Sergei Pourmal, Nikola P. Pavletich · eLife · 2015 · 134 citations · Full text

, , +14

Molecular basis of microhomology-mediated end-joining by purified full-length Polθ

Samuel J. Black, Ahmet Y. Ozdemir, Ekaterina Kashkina et al. · Nature Communications · 2019 · 116 citations · Full text

, , +17

1–5 of 29

Authors

183

  1. CW
    Claire Wyman

    Erasmus MC, Netherlands

    3 publications · 685 citations

    3

    h-index

  2. PĆ
    Petr Ćejka

    Università della Svizzera italiana, Switzerland

    2 publications · 75 citations

    2

    h-index

  3. RK
    Roland Kanaar

    Erasmus MC, Netherlands

    2 publications · 569 citations

    2

    h-index

  4. CD
    Cees Dekker

    Delft University of Technology, Netherlands

    2 publications · 569 citations

    2

    h-index

  5. GJ
    Gareth J. Williams

    Bangor University, United Kingdom

    1 publications · 144 citations

    1

    h-index

1–5 of 183

Institutions

79

  1. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    12 publications

    275 citations

  2. Columbia University

    New York, United States

    2 h-index

    6 publications

    261 citations

  3. Board of the Swiss Federal Institutes of Technology

    Zurich, Switzerland

    2 h-index

    9 publications

    362 citations

  4. Erasmus MC

    Rotterdam, The Netherlands

    2 h-index

    7 publications

    547 citations

  5. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    2 h-index

    3 publications

    109 citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    5 publications

    710 citations

  7. KU Leuven

    Leuven, Belgium

    2 h-index

    10 publications

    360 citations

  8. Université Paris-Sud

    Orsay, France

    2 h-index

    3 publications

    109 citations

1–8 of 79

Venues

  1. Nucleic Acids Research

    5 publications · 200 citations

    5

    h-index

  2. Nature Communications

    3 publications · 191 citations

    3

    h-index

  3. Cell Reports

    3 publications · 88 citations

    3

    h-index

  4. Journal of Molecular Biology

    JMB · 2 publications · 61 citations

    2

    h-index

  5. Molecular Cell

    2 publications · 620 citations

    2

    h-index

1–5