Concepedia

Protein Interaction Design

Protein Interaction Design is a computational or experimental methodology aimed at engineering specific, functional interactions between proteins by rationally specifying interface residues, binding affinities, and complex topologies to achieve predefined biological or structural outcomes.

27

Publications

2.3K

Citations

227

Authors

88

Institutions

Publications per year

2017–2026

7

Parents

Publications

27

Design of protein-interaction specificity gives selective bZIP-binding peptides

Gevorg Grigoryan, Amy E. Keating · Nature · 2009 · 346 citations · Full text

, , +14

Rational design of faster associating and tighter binding protein complexes.

Gideon Schreiber, Tzvia Selzer, Shira Albeck · Nature Structural Biology · 2000 · 304 citations

, , +16

An in vivo library-versus-library selection of optimized protein–protein interactions

Joelle N. Pelletier, Katja M. Arndt, Andreas Plückthun et al. · Nature Biotechnology · 1999 · 166 citations

, , +14

Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

Sarel J. Fleishman, Timothy A. Whitehead, Eva‐Maria Strauch et al. · Journal of Molecular Biology · 2011 · 136 citations · Full text

, , +15

EvoEF2: accurate and fast energy function for computational protein design

Xiaoqiang Huang, Robin Pearce, Yang Zhang · Bioinformatics · 2019 · 131 citations · Full text

, , +17

1–5 of 27

Authors

227

  1. SA
    Shira Albeck

    Weizmann Institute of Science, Israel

    2 publications · 358 citations

    2

    h-index

  2. LS
    Luís Serrano

    Centre for Genomic Regulation, Spain

    2 publications · 46 citations

    2

    h-index

  3. BK
    Brian Kuhlman

    University of North Carolina at Chapel Hill, United States

    2 publications · 208 citations

    2

    h-index

  4. LL
    Luhua Lai

    Peking University, China

    2 publications · 105 citations

    2

    h-index

  5. RP
    Robin Pearce

    University of Michigan, United States

    2 publications · 224 citations

    2

    h-index

1–5 of 227

Institutions

88

  1. Weizmann Institute of Science

    Rehovot, Israel

    3 h-index

    15 publications

    2K citations

  2. Beijing National Laboratory for Molecular Sciences

    Beijing, China

    2 h-index

    8 publications

    550 citations

  3. Hebrew University of Jerusalem

    Jerusalem, Israel

    2 h-index

    5 publications

    538 citations

  4. Université Paris-Sud

    Orsay, France

    2 h-index

    4 publications

    498 citations

  5. State Key Laboratory for Structural Chemistry of Unstable and Stable Species

    Beijing, China

    2 h-index

    8 publications

    550 citations

  6. University of Michigan

    Ann Arbor, United States

    2 h-index

    5 publications

    503 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    4 publications

    498 citations

  8. University of Zurich

    Zurich, Switzerland

    2 h-index

    4 publications

    550 citations

1–8 of 88

Venues

  1. Journal of Molecular Biology

    JMB · 5 publications · 405 citations

    5

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 241 citations

    3

    h-index

  3. PLoS Computational Biology

    2 publications · 172 citations

    2

    h-index

  4. Protein Engineering Design and Selection

    PEDS · 1 publications · 12 citations

    1

    h-index

  5. Nucleic Acids Research

    1 publications · 34 citations

    1

    h-index

1–5