An in vivo library-versus-library selection of optimized protein–protein interactions

A novel genetic system to detect protein–protein interactions

Stanley Fields, Ok-kyu Song · Nature · 1989 · 6.1K citations

Interactomics, Natural Sciences, Protein Analysis +7

Filamentous Fusion Phage: Novel Expression Vectors That Display Cloned Antigens on the Virion Surface

George P. Smith · Science · 1985 · 4K citations

Viral Replication, Filamentous Fusion Phage, Reverse Genetics +21

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest.

Cheng‐Ting Chien, Paul L. Bartel, Rolf Sternglanz et al. · Proceedings of the National Academy of Sciences · 1991 · 1.5K citations

Genetics, Molecular Biology, Reporter Gene +22

X-Ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil

Erin K. O’Shea, Juli D. Klemm, Peter S. Kim et al. · Science · 1991 · 1.4K citations

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

Micheline Fromont‐Racine, Jean‐Christophe Rain, Pierre Legrain · Nature Genetics · 1997 · 900 citations

Long-read Sequencing, Functional Genomics, Engineering +15