Concepedia

Protein Complex Activation

Protein Complex Activation is a biochemical process whereby a multi-protein assembly transitions into a functionally active state through conformational changes, post-translational modifications, or ligand binding that enable its biological activity.

105

Publications

11.1K

Citations

553

Authors

211

Institutions

Publications per year

2017–2026

16

Parents

Publications

105

Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain

Li Deng, Chen Wang, Erika Spencer et al. · Cell · 2000 · 1.9K citations · Full text

, , +16

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

Hongwu Chen, Richard J. Lin, R. Louis Schiltz et al. · Cell · 1997 · 1.5K citations · Full text

, , +16

Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo

Andrew B. Lassar, Robert L. Davis, Woodring E. Wright et al. · Cell · 1991 · 867 citations

, , +10

The Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation

Sandra W. Cowan‐Jacob, Gabriele Fendrich, Paul W. Manley et al. · Structure · 2005 · 346 citations · Full text

, , +14

p40<i>phox</i>, a third cytosolic component of the activation complex of the NADPH oxidase to contain <i>src</i> homology 3 domains

Frans B. Wientjes, J. Justin Hsuan, Nicholas F. Totty et al. · Biochemical Journal · 1993 · 296 citations · Full text

, , +17

1–5 of 105

Authors

553

  1. CT
    Charles T. Esmon

    Oklahoma Medical Research Foundation, United States

    5 publications · 481 citations

    5

    h-index

  2. AR
    Alireza R. Rezaie

    Saint Louis University, United States

    5 publications · 263 citations

    5

    h-index

  3. NL
    N L Esmon

    Oklahoma Medical Research Foundation, United States

    2 publications · 82 citations

    2

    h-index

  4. AM
    Alan M. Jones

    University of North Carolina at Chapel Hill, United States

    2 publications · 147 citations

    2

    h-index

  5. AA
    Ale Algra

    University Medical Center Utrecht, Netherlands

    2 publications · 140 citations

    2

    h-index

1–5 of 553

Institutions

211

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    8 h-index

    15 publications

    7.1K citations

  2. University College London

    London, United Kingdom

    4 h-index

    8 publications

    744 citations

  3. Inserm

    Paris, France

    4 h-index

    18 publications

    723 citations

  4. University of Michigan

    Ann Arbor, United States

    4 h-index

    21 publications

    1.2K citations

  5. Washington University in St. Louis

    St Louis, United States

    4 h-index

    11 publications

    370 citations

  6. Oklahoma Medical Research Foundation

    Oklahoma City, United States

    3 h-index

    7 publications

    479 citations

  7. Saint Louis University

    St Louis, United States

    3 h-index

    6 publications

    150 citations

  8. University Medical Center Utrecht

    Utrecht, The Netherlands

    3 h-index

    7 publications

    675 citations

1–8 of 211

Venues

  1. Journal of Biological Chemistry

    JBC · 12 publications · 804 citations

    12

    h-index

  2. Biochemical Journal

    BJ · 4 publications · 355 citations

    4

    h-index

  3. Structure

    4 publications · 505 citations

    4

    h-index

  4. Thrombosis and Haemostasis

    4 publications · 320 citations

    4

    h-index

  5. The Journal of Immunology

    JI · 4 publications · 242 citations

    4

    h-index

1–5