Gabriele Fendrich

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Ellen Weisberg, Paul W. Manley, Werner Breitenstein et al. · Cancer Cell · 2005 · 1.5K citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +6

Targeting Bcr–Abl by combining allosteric with ATP-binding-site inhibitors

Jianming Zhang, Francisco Adrián, Wolfgang Jahnke et al. · Nature · 2010 · 599 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

The Crystal Structure of a c-Src Complex in an Active Conformation Suggests Possible Steps in c-Src Activation

Sandra W. Cowan‐Jacob, Gabriele Fendrich, Paul W. Manley et al. · Structure · 2005 · 346 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

Sandra W. Cowan‐Jacob, Gabriele Fendrich, Andreas Floersheimer et al. · Acta Crystallographica Section D Biological Crystallography · 2006 · 289 citations · Full text

Medicine, Molecular Biology, Pharmacology +13

Extended kinase profile and properties of the protein kinase inhibitor nilotinib

Paul W. Manley, Peter Drueckes, Gabriele Fendrich et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2009 · 222 citations

Life Sciences, Medicinal Chemistry, Pharmacology +12