Pre-specified Subgroup Effects
Pre-Specified Subgroup Effects is a type of treatment effect heterogeneity analysis in which the subgroups of interest are defined a priori based on scientific rationale or clinical relevance before the initiation of the study, thereby distinguishing it from data-driven or post hoc subgroup explorations.
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2017–2026
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Subgroup analysis and other (mis)uses of baseline data in clinical trials
Susan F. Assmann, Stuart Pocock, Laura E. Enos et al. · The Lancet · 2000 · 1.2K citations
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University Medical Center Utrecht
Utrecht, The Netherlands
7 h-index
14 publications
530 citations

McMaster University
Hamilton, Canada
7 h-index
37 publications
5.3K citations
Harvard University
Cambridge, United States
7 h-index
11 publications
624 citations
University of Michigan
Ann Arbor, United States
7 h-index
12 publications
878 citations

University of Toronto
Toronto, Canada
7 h-index
7 publications
414 citations
Stanford University
Stanford, United States
6 h-index
9 publications
597 citations
University of North Carolina at Chapel Hill
Chapel Hill, United States
6 h-index
14 publications
402 citations
Erasmus MC
Rotterdam, The Netherlands
6 h-index
11 publications
786 citations
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7 publications · 1.8K citations
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6 publications · 231 citations
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DIA · 4 publications · 94 citations
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4 publications · 716 citations
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AHJ · 4 publications · 330 citations
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