Clinical Trials

An exploratory test for an excess of significant findings

John P. A. Ioannidis, Thomas A Trikalinos · 2007 · 761 citations

The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The Systolic Blood Pressure Intervention Trial (SPRINT)

Walter T. Ambrosius, Kaycee M. Sink, Capri G. Foy et al. · 2014 · 531 citations · Full text

Beyond the intention-to-treat in comparative effectiveness research

Miguel A. Hernán, Sonia Hernández–Dı́az · 2011 · 493 citations · Full text

Key cost drivers of pharmaceutical clinical trials in the United States

Aylin Sertkaya, Hui–Hsing Wong, Amber Jessup et al. · 2016 · 397 citations

Summarizing historical information on controls in clinical trials

Beat Neuenschwander, Gorana Capkun-Niggli, Michael Branson et al. · 2010 · 371 citations