Concepedia

Polyvalent Binding

Polyvalent Binding is a molecular interaction mechanism in which multiple ligands on one entity simultaneously bind to multiple receptors on another, thereby enhancing binding affinity and specificity through cooperative multivalent effects.

103

Publications

6.9K

Citations

366

Authors

157

Institutions

Publications per year

2017–2026

7

Variants

Multivalent Binding

Parents

Publications

103

Fluorescent Ag Clusters via a Protein-Directed Approach as a Hg(II) Ion Sensor

Cunlan Guo, Joseph Irudayaraj · Analytical Chemistry · 2011 · 421 citations

, , +17

Polyacrylamides Bearing Pendant α-Sialoside Groups Strongly Inhibit Agglutination of Erythrocytes by Influenza Virus:  The Strong Inhibition Reflects Enhanced Binding through Cooperative Polyvalent Interactions

George B. Sigal, Mathai Mammen, Georg Dahmann et al. · Journal of the American Chemical Society · 1996 · 340 citations

, , +13

Osmotic pressure inhibition of DNA ejection from phage

Alex Evilevitch, Laurence Lavelle, Charles M. Knobler et al. · Proceedings of the National Academy of Sciences · 2003 · 334 citations · Full text

, , +13

Designing a polyvalent inhibitor of anthrax toxin

Michaël Mourez, Ravi S. Kane, Jeremy Mogridge et al. · Nature Biotechnology · 2001 · 272 citations

, , +12

Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes.

Ira Mellman, Helen Plutner · The Journal of Cell Biology · 1984 · 255 citations · Full text

, , +17

1–5 of 103

Authors

366

  1. RS
    Ravi S. Kane

    Rensselaer Polytechnic Institute, United States

    4 publications · 469 citations

    4

    h-index

  2. GM
    George M. Whitesides

    Harvard University, United States

    4 publications · 1K citations

    4

    h-index

  3. JM
    Jeremy Mogridge

    University of Toronto, Canada

    4 publications · 469 citations

    4

    h-index

  4. MM
    Mathai Mammen

    Harvard University, United States

    3 publications · 649 citations

    3

    h-index

  5. MS
    Markus Streiff

    Novartis (Switzerland), Switzerland

    3 publications · 108 citations

    3

    h-index

1–5 of 366

Institutions

157

  1. Harvard University

    Cambridge, United States

    8 h-index

    37 publications

    6.7K citations

  2. University of Toronto

    Toronto, Canada

    5 h-index

    19 publications

    2K citations

  3. Scripps Research Institute

    San Diego, United States

    4 h-index

    9 publications

    648 citations

  4. Canada Research Chairs

    Ottawa, Canada

    4 h-index

    15 publications

    1K citations

  5. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    15 publications

    2K citations

  6. Rensselaer Polytechnic Institute

    Troy, United States

    3 h-index

    20 publications

    1.2K citations

  7. The University of Melbourne

    Melbourne, Australia

    3 h-index

    7 publications

    178 citations

  8. Novartis (Switzerland)

    Basel, Switzerland

    3 h-index

    14 publications

    508 citations

1–8 of 157

Venues

  1. Journal of the American Chemical Society

    JACS · 11 publications · 1K citations

    11

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 1.1K citations

    6

    h-index

  3. PubMed

    Repository · 4 publications · 117 citations

    4

    h-index

  4. Angewandte Chemie International Edition

    4 publications · 453 citations

    4

    h-index

  5. Journal of Biological Chemistry

    JBC · 3 publications · 102 citations

    3

    h-index

1–5