Ira Mellman

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan, Shannon J. Turley, Dorothee Nickles et al. · Nature · 2018 · 5.2K citations · Full text

Tumor Biology, Cancer Immunosurveillance, Tumour Response +12

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

Roy S. Herbst, Jean‐Charles Soria, Marcin Kowanetz et al. · Nature · 2014 · 5.2K citations

Medicine, Biomarker Target, Anti-pd-l1 Antibody Mpdl3280a +10

Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

Roberto Lande, Josh Gregorio, Valeria Facchinetti et al. · Nature · 2007 · 1.8K citations

Inflammation, Plasmacytoid Dendritic Cells, Immunology +4

T cell costimulatory receptor CD28 is a primary target for PD-1–mediated inhibition

Enfu Hui, Jeanne Cheung, Jing Zhu et al. · Science · 2017 · 1.6K citations · Full text

Programmed Cell Death-1, Adaptive Immune System, T-regulatory Cell +18

The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research

Martin A. Cheever, James P. Allison, Andrea Stern Ferris et al. · Clinical Cancer Research · 2009 · 1.4K citations · Full text

Cancer Antigens, Immunology, Immunoediting +19