Concepedia

Polygenic Models

Polygenic Models is a statistical genetics framework that posits a trait or disease is influenced by the cumulative effects of a large number of genetic loci, each contributing a small, additive effect, contrasting with models that attribute inheritance to a single major gene or environmental factors.

980

Publications

72.2K

Citations

6.7K

Authors

1.7K

Institutions

Publications per year

2017–2026

273

Variants

Polygenic Inheritance Models

Parents

Publications

980

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

Manuel A. R. Ferreira · Nature · 2009 · 5K citations · Full text

, , +14

SEXUAL DIMORPHISM, SEXUAL SELECTION, AND ADAPTATION IN POLYGENIC CHARACTERS

Russell Lande · Evolution · 1980 · 1.7K citations · Full text

, , +16

Leveraging Polygenic Functional Enrichment to Improve GWAS Power

Gleb Kichaev, Gaurav Bhatia, Po‐Ru Loh et al. · The American Journal of Human Genetics · 2018 · 1.1K citations · Full text

, , +14

Polygenic susceptibility to breast cancer and implications for prevention

Paul D.P. Pharoah, Antonis C. Antoniou, Martin Bobrow et al. · Nature Genetics · 2002 · 902 citations · Full text

, , +12

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Amit V. Khera, Mark Chaffin, Kaitlin H. Wade et al. · Cell · 2019 · 829 citations · Full text

, , +14

1–5 of 980

Authors

6.7K

  1. DF
    Douglas F. Easton

    University of Cambridge, United Kingdom

    12 publications · 3K citations

    12

    h-index

  2. AC
    Antonis C. Antoniou

    University of Cambridge, United Kingdom

    11 publications · 3K citations

    11

    h-index

  3. PM
    Peter M. Visscher

    The University of Queensland, Australia

    11 publications · 2.4K citations

    11

    h-index

  4. PD
    Paul D.P. Pharoah

    University of Cambridge, United Kingdom

    10 publications · 2.8K citations

    10

    h-index

  5. NG
    Nicholas G. Martin

    QIMR Berghofer Medical Research Institute, Australia

    9 publications · 2.1K citations

    10

    h-index

1–5 of 6.7K

Institutions

1.7K

  1. Harvard University

    Cambridge, United States

    39 h-index

    372 publications

    57.8K citations

  2. Broad Institute

    Cambridge, United States

    33 h-index

    249 publications

    109.8K citations

  3. University College London

    London, United Kingdom

    27 h-index

    77 publications

    43.9K citations

  4. Brigham and Women's Hospital

    Boston, United States

    27 h-index

    149 publications

    19.5K citations

  5. Massachusetts General Hospital

    Boston, United States

    25 h-index

    121 publications

    56.7K citations

  6. University of Cambridge

    Cambridge, United Kingdom

    24 h-index

    121 publications

    16.8K citations

  7. Johns Hopkins University

    Baltimore, United States

    22 h-index

    98 publications

    10.9K citations

  8. University of Edinburgh

    Edinburgh, United Kingdom

    22 h-index

    113 publications

    33.6K citations

1–8 of 1.7K

Venues

  1. Genetics

    53 publications · 5.2K citations

    37

    h-index

  2. PubMed

    Repository · 32 publications · 1.6K citations

    20

    h-index

  3. Genetic Epidemiology

    29 publications · 1.8K citations

    19

    h-index

  4. Evolution

    20 publications · 3.5K citations

    16

    h-index

  5. PLoS ONE

    17 publications · 728 citations

    14

    h-index

1–5