Mark Chaffin

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

Amit V. Khera, Mark Chaffin, Krishna G. Aragam et al. · Nature Genetics · 2018 · 3.1K citations

Life Sciences, Genetics, Molecular Genetics +16

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Daniel Taliun, Daniel Harris, Michael D. Kessler et al. · Nature · 2021 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Transfer learning enables predictions in network biology

Christina V. Theodoris, Ling Xiao, Anant Chopra et al. · Nature · 2023 · 1K citations · Full text

Life Sciences, Biology, Systems Biology +9

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

Amit V. Khera, Mark Chaffin, Kaitlin H. Wade et al. · Cell · 2019 · 829 citations · Full text

Life Sciences, Biostatistics, Genetics +14

Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

Stephen J. Fleming, Mark Chaffin, Alessandro Arduini et al. · Nature Methods · 2023 · 813 citations

Life Sciences, Bioengineering, Cell Biology +9