Segregation Analysis is a family-based statistical method in genetic epidemiology that models the distribution of phenotypes or genotypes within pedigrees to test whether the observed familial aggregation is consistent with specific modes of inheritance (e.g., major-gene, polygenic, environmental) and to estimate the underlying genetic parameters.
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A General Model for the Genetic Analysis of Pedigree Data
Robert C. Elston, Jason A. Stewart · Human Heredity · 1971 · 1.6K citations
Income Inequality and Income Segregation
Sean F. Reardon, Kendra Bischoff · American Journal of Sociology · 2011 · 1.1K citations
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