Concepedia

Poly(adp-ribose) Recognition

Poly(ADP-Ribose) Recognition is the specific molecular process by which proteins or protein domains selectively bind to poly(ADP-ribose) chains synthesized by PARP enzymes in response to DNA damage, thereby facilitating the recruitment and coordination of downstream repair factors at lesion sites.

201

Publications

18.3K

Citations

925

Authors

304

Institutions

Publications per year

2017–2026

62

Parents

Publications

201

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III–transcribed RNA intermediate

Andrea Ablasser, Franz Bauernfeind, Gunther Hartmann et al. · Nature Immunology · 2009 · 868 citations · Full text

, , +15

Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1

Marie-France Langelier, Jamie L. Planck, Swati Roy et al. · Science · 2012 · 681 citations

, , +17

Poly ADP-ribose and ADP-ribosylation of proteins

Osamu Hayaishi · Trends in Biochemical Sciences · 1976 · 573 citations

, , +12

Poly(ADP-ribose) Binds to Specific Domains in DNA Damage Checkpoint Proteins

Jutta M. Pleschke, Hanna E. Kleczkowska, Mark Strohm et al. · Journal of Biological Chemistry · 2000 · 542 citations · Full text

, , +14

The macro domain is an ADP‐ribose binding module

Georgios Ioannis Karras, Georg Kustatscher, Heeran R Buhecha et al. · The EMBO Journal · 2005 · 507 citations · Full text

, , +13

1–5 of 201

Authors

925

  1. FR
    Felix R. Althaus

    University of Zurich, Switzerland

    13 publications · 1.2K citations

    11

    h-index

  2. AK
    Anthony K. L. Leung

    Johns Hopkins University, United States

    9 publications · 491 citations

    9

    h-index

  3. MM
    Maria Malanga

    University of Zurich, Switzerland

    9 publications · 667 citations

    9

    h-index

  4. IA
    Ivan Ahel

    University of Oxford, United Kingdom

    8 publications · 974 citations

    8

    h-index

  5. AB
    Alexander Bürkle

    University of Konstanz, Germany

    7 publications · 660 citations

    7

    h-index

1–5 of 925

Institutions

304

  1. University of Zurich

    Zurich, Switzerland

    11 h-index

    46 publications

    6K citations

  2. Johns Hopkins University

    Baltimore, United States

    11 h-index

    48 publications

    8.5K citations

  3. Johns Hopkins Medicine

    Baltimore, United States

    10 h-index

    26 publications

    4.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    39 publications

    6.1K citations

  5. Université Laval

    Québec, Canada

    9 h-index

    40 publications

    6.1K citations

  6. The University of Texas Southwestern Medical Center

    Dallas, United States

    7 h-index

    27 publications

    1.5K citations

  7. Georgetown University

    Washington, United States

    6 h-index

    21 publications

    668 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    10 publications

    543 citations

1–8 of 304

Venues

  1. Journal of Biological Chemistry

    JBC · 23 publications · 3.3K citations

    22

    h-index

  2. Nucleic Acids Research

    11 publications · 1K citations

    11

    h-index

  3. Nature Communications

    9 publications · 669 citations

    9

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 8 publications · 741 citations

    8

    h-index

  5. Journal of Molecular Biology

    JMB · 8 publications · 674 citations

    8

    h-index

1–5