Concepedia

Pleiotropic Lethal Effects

Pleiotropic Lethal Effects is a genetic phenomenon in which a single allele exerts multiple phenotypic effects, one of which includes causing organismal death, thereby coupling lethal consequences with other non-lethal developmental or physiological disruptions.

164

Publications

12.5K

Citations

723

Authors

255

Institutions

Publications per year

2017–2026

18

Parents

Publications

164

Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.

Jennifer V. Schmidt, Gloria H. Su, Janardan K. Reddy et al. · Proceedings of the National Academy of Sciences · 1996 · 899 citations

, , +17

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

S. P. Flanagan · Genetics Research · 1966 · 856 citations · Full text

, , +16

Thalidomide promotes degradation of SALL4, a transcription factor implicated in Duane Radial Ray syndrome

Katherine A. Donovan, An Jian, Radosław P. Nowak et al. · eLife · 2018 · 517 citations · Full text

, , +13

Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites.

Louis Schofield, Fiona Hackett · The Journal of Experimental Medicine · 1993 · 506 citations · Full text

, , +17

ELO2 and ELO3, Homologues of theSaccharomyces cerevisiae ELO1 Gene, Function in Fatty Acid Elongation and Are Required for Sphingolipid Formation

Chan-Seok Oh, David A. Toke, Suzanne Mandala et al. · Journal of Biological Chemistry · 1997 · 485 citations · Full text

, , +17

1–5 of 164

Authors

723

  1. MS
    Marvin S. Legator

    The University of Texas Medical Branch at Galveston, United States

    3 publications · 56 citations

    3

    h-index

  2. WG
    W.M. Generoso

    Oak Ridge National Laboratory, United States

    3 publications · 210 citations

    3

    h-index

  3. GS
    Gregory S. Barsh

    Stanford University, United States

    3 publications · 563 citations

    3

    h-index

  4. AV
    Andreas Vilcinskas

    Justus-Liebig-Universität Gießen, Germany

    2 publications · 71 citations

    2

    h-index

  5. WF
    W. F. Hollander

    Iowa State University, United States

    2 publications · 56 citations

    2

    h-index

1–5 of 723

Institutions

255

  1. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    17 publications

    1.2K citations

  2. University of Edinburgh

    Edinburgh, United Kingdom

    5 h-index

    36 publications

    4K citations

  3. Medical Research Council

    London, United Kingdom

    4 h-index

    8 publications

    1K citations

  4. Harvard University

    Cambridge, United States

    4 h-index

    11 publications

    2.3K citations

  5. Nagoya University

    Nagoya, Japan

    4 h-index

    18 publications

    1.4K citations

  6. Oak Ridge National Laboratory

    Oak Ridge, United States

    4 h-index

    18 publications

    2.1K citations

  7. Johns Hopkins University

    Baltimore, United States

    3 h-index

    13 publications

    784 citations

  8. Yale University

    New Haven, United States

    3 h-index

    7 publications

    316 citations

1–8 of 255

Venues

  1. Journal of Bacteriology

    JB · 15 publications · 587 citations

    13

    h-index

  2. Genetics

    11 publications · 1K citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 11 publications · 1.8K citations

    11

    h-index

  4. Journal of Biological Chemistry

    JBC · 7 publications · 892 citations

    7

    h-index

  5. 5

    h-index

1–5