Concepedia

Phenyl Replacement

Phenyl Replacement is a nonclassical bioisosteric strategy that involves substituting a phenyl ring with a structurally distinct moiety while maintaining or modulating biological activity through comparable spatial, electronic, or pharmacophoric properties.

149

Publications

8K

Citations

867

Authors

223

Institutions

Publications per year

2017–2026

28

Parents

Publications

149

Blue and Near-UV Phosphorescence from Iridium Complexes with Cyclometalated Pyrazolyl or <i>N</i>-Heterocyclic Carbene Ligands

T. Sajoto, Peter I. Djurovich, Arnold Tamayo et al. · Inorganic Chemistry · 2005 · 656 citations

, , +17

Highly Efficient Ruthenium Catalysts for the Formation of Tetrasubstituted Olefins via Ring-Closing Metathesis

Ian C. Stewart, Thay Ung, Alexandre A. Pletnev et al. · Organic Letters · 2007 · 304 citations

, , +13

A New Highly Efficient Ruthenium Metathesis Catalyst This work was supported by the Fonds der Chemischen Industrie.

Hideaki Wakamatsu, Siegfried Blechert · Angewandte Chemie International Edition · 2002 · 282 citations · Full text

, , +13

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA <sub>2</sub> Inhibitor

Nicholas D. Measom, Kenneth Down, David J. Hirst et al. · ACS Medicinal Chemistry Letters · 2016 · 246 citations · Full text

, , +17

Designing Higher Surface Area Metal–Organic Frameworks: Are Triple Bonds Better Than Phenyls?

Omar K. Farha, Christopher E. Wilmer, Ibrahim Eryazici et al. · Journal of the American Chemical Society · 2012 · 221 citations

, , +12

1–5 of 149

Authors

867

  1. DS
    Dieter Steinhilber

    Goethe University Frankfurt, Germany

    3 publications · 75 citations

    3

    h-index

  2. RK
    Robert Kuhnert

    Leipzig University, Germany

    2 publications · 33 citations

    2

    h-index

  3. BH
    Bettina Hofmann

    Goethe University Frankfurt, Germany

    2 publications · 33 citations

    2

    h-index

  4. MŌ
    Masao Ōkubo

    Saga University, Japan

    2 publications · 28 citations

    2

    h-index

  5. MB
    Menyhárt B. Sárosi

    Leipzig University, Germany

    2 publications · 33 citations

    2

    h-index

1–5 of 867

Institutions

223

  1. University of Hong Kong

    Pok Fu Lam, Hong Kong

    3 h-index

    11 publications

    1K citations

  2. Institute of Molecular Functional Materials

    Hong Kong, China

    3 h-index

    9 publications

    767 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    14 publications

    298 citations

  4. Merck Canada Inc. (Canada)

    Kirkland, Canada

    3 h-index

    36 publications

    1.8K citations

  5. Princeton University

    Princeton, United States

    3 h-index

    12 publications

    4.9K citations

  6. Goethe University Frankfurt

    Frankfurt am Main, Germany

    3 h-index

    16 publications

    519 citations

  7. Inserm

    Paris, France

    3 h-index

    21 publications

    520 citations

  8. Leipzig University

    Leipzig, Germany

    3 h-index

    11 publications

    180 citations

1–8 of 223

Venues

  1. Journal of Medicinal Chemistry

    17 publications · 1.1K citations

    15

    h-index

  2. Chemistry - A European Journal

    6 publications · 242 citations

    6

    h-index

  3. Inorganic Chemistry

    5 publications · 937 citations

    5

    h-index

  4. The Journal of Organic Chemistry

    JOC · 4 publications · 212 citations

    4

    h-index

  5. 4

    h-index

1–5