David J. Hirst

Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA ₂ Inhibitor

Nicholas D. Measom, Kenneth Down, David J. Hirst et al. · ACS Medicinal Chemistry Letters · 2016 · 246 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain

Robert P. Law, Stephen J. Atkinson, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2018 · 118 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Christopher R. Wellaway, Dominique Amans, Paul Bamborough et al. · Journal of Medicinal Chemistry · 2020 · 71 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Highly Selective Allylborations of Aldehydes Using α,α‐Disubstituted Allylic Pinacol Boronic Esters

Matthew J. Hesse, Stéphanie Essafi, Charlotte G. Watson et al. · Angewandte Chemie International Edition · 2014 · 66 citations · Full text

Natural Sciences, Chemistry, Catalysis +9

Somatosensory and auditory brain stem conduction after head injury

Kenneth W. Lindsay, A. Paşaoğlu, David J. Hirst et al. · Neurosurgery · 1990 · 61 citations

Medicine, Neurology, Neuroscience +15