Concepedia

Ph Adjustment

pH Adjustment is a formulation operation in parenteral dosage form development that involves the controlled modification of a preparation’s hydrogen ion concentration, typically by adding pharmaceutically acceptable acids, bases, or buffers, to achieve a specified pH that optimizes drug stability, solubility, compatibility, and physiological tolerability.

429

Publications

21.3K

Citations

1.3K

Authors

466

Institutions

Publications per year

2017–2026

36

Parents

Children

Publications

429

Intracellular pH and its Regulation

F. Andrew Smith, John A. Raven · Annual Review of Plant Physiology · 1979 · 612 citations

, , +13

Akt activation by growth factors is a multiple-step process: the role of the PH domain

Alfonso Bellacosa, Tung O. Chan, Naheed N. Ahmed et al. · Oncogene · 1998 · 542 citations

, , +15

Optimization of pH controlled liquid hot water pretreatment of corn stover

Nathan S. Mosier, Richard Hendrickson, Nancy W. Y. Ho et al. · Bioresource Technology · 2005 · 536 citations

, , +9

Nomograms for correction of blood Po2, Pco2, pH, and base excess for time and temperature.

Guy Kelman, J. F. Nunn · Journal of Applied Physiology · 1966 · 428 citations

, , +5

Independent and dependent variables of acid-base control

Peter A. Stewart · Respiration Physiology · 1978 · 423 citations

, , +11

1–5 of 429

Authors

1.3K

  1. RG
    Roger G. Bates

    University of Florida, United States

    9 publications · 518 citations

    9

    h-index

  2. EG
    Elisabetta Gianazza

    University of Milan, Italy

    7 publications · 346 citations

    7

    h-index

  3. PG
    Pier Giorgio Righetti

    University of Milan, Italy

    7 publications · 346 citations

    7

    h-index

  4. FC
    F. Celentano

    University of Milan, Italy

    6 publications · 285 citations

    6

    h-index

  5. SR
    Sandra Rondinini

    University of Milan, Italy

    3 publications · 66 citations

    3

    h-index

1–5 of 1.3K

Institutions

466

  1. University of Milan

    Milan, Italy

    11 h-index

    45 publications

    1.8K citations

  2. University of Michigan

    Ann Arbor, United States

    5 h-index

    9 publications

    455 citations

  3. University at Buffalo, State University of New York

    Buffalo, United States

    4 h-index

    11 publications

    326 citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    10 publications

    739 citations

  5. The Ohio State University

    Columbus, United States

    4 h-index

    9 publications

    431 citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    7 publications

    114 citations

  7. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    6 publications

    554 citations

  8. National Heart Lung and Blood Institute

    Bethesda, United States

    3 h-index

    3 publications

    514 citations

1–8 of 466

Venues

  1. PubMed

    Repository · 15 publications · 400 citations

    12

    h-index

  2. Analytica Chimica Acta

    9 publications · 194 citations

    9

    h-index

  3. Analytical Chemistry

    8 publications · 387 citations

    8

    h-index

  4. 7

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  5. Analytical Biochemistry

    7 publications · 438 citations

    7

    h-index

1–5