Concepedia

Peripheral Tolerance Development

Peripheral Tolerance Development is a biological process in the immune system ontogeny that refers to the establishment of self-tolerance in mature T cells within peripheral tissues through mechanisms that prevent autoimmunity while preserving immune responsiveness.

199

Publications

18.2K

Citations

1K

Authors

347

Institutions

Publications per year

2017–2026

16

Parents

Publications

199

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah Brown et al. · The Journal of Experimental Medicine · 2009 · 2K citations · Full text

, , +16

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

Elizabeth R. Kearney, Kathryn A. Pape, Dennis Y. Loh et al. · Immunity · 1994 · 946 citations

, , +14

FOXP3: Of Mice and Men

Steven F. Ziegler · Annual Review of Immunology · 2005 · 917 citations

, , +17

Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance

Yongsheng Li, Li X, Xin Xiao Zheng et al. · Nature Medicine · 1999 · 750 citations

, , +17

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

Catherine A. Sabatos, Sumone Chakravarti, Anna Schubart et al. · Nature Immunology · 2003 · 619 citations

, , +16

1–5 of 199

Authors

1K

  1. JS
    Joan Stein‐Streilein

    Harvard University, United States

    6 publications · 1K citations

    6

    h-index

  2. TN
    Takahiko Nakamura

    Kobe University, Japan

    4 publications · 438 citations

    4

    h-index

  3. HL
    Howard L. Weiner

    Brigham and Women's Hospital, United States

    4 publications · 384 citations

    4

    h-index

  4. GJ
    Gordon J. Freeman

    Dana-Farber Cancer Institute, United States

    3 publications · 3K citations

    3

    h-index

  5. LZ
    Li Zhang

    University of California, San Francisco, United States

    3 publications · 295 citations

    3

    h-index

1–5 of 1K

Institutions

347

  1. Harvard University

    Cambridge, United States

    20 h-index

    88 publications

    30.4K citations

  2. Brigham and Women's Hospital

    Boston, United States

    12 h-index

    39 publications

    15.4K citations

  3. Massachusetts Eye and Ear Infirmary

    Boston, United States

    8 h-index

    22 publications

    3.7K citations

  4. Smith-Kettlewell Eye Research Institute

    San Francisco, United States

    8 h-index

    22 publications

    3.7K citations

  5. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    33 publications

    7.5K citations

  6. National Institutes of Health

    Bethesda, United States

    7 h-index

    20 publications

    3.9K citations

  7. Inserm

    Paris, France

    7 h-index

    26 publications

    986 citations

  8. National Cancer Institute

    Bethesda, United States

    6 h-index

    16 publications

    3.6K citations

1–8 of 347

Venues

  1. The Journal of Immunology

    JI · 41 publications · 2.6K citations

    27

    h-index

  2. The Journal of Experimental Medicine

    16 publications · 4.1K citations

    16

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 16 publications · 1.9K citations

    15

    h-index

  4. European Journal of Immunology

    EJI · 11 publications · 817 citations

    11

    h-index

  5. PubMed

    Repository · 9 publications · 500 citations

    9

    h-index

1–5