Concepedia

Peptide Degradation

Peptide Degradation is a biomaterial degradation process in which peptide bonds within a polypeptide chain are selectively hydrolyzed or enzymatically cleaved, distinguishing it from broader protein degradation mechanisms by its focus on short-chain amino acid sequences and site-specific breakdown pathways.

792

Publications

48.9K

Citations

2.9K

Authors

823

Institutions

Publications per year

2017–2026

101

Parents

Publications

792

A gas-liquid solid phase peptide and protein sequenator.

Rodney M. Hewick, Michael W. Hunkapiller, Leroy Hood et al. · Journal of Biological Chemistry · 1981 · 2.2K citations · Full text

, , +17

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.

Terrence L. Geiger, Steven Clarke · Journal of Biological Chemistry · 1987 · 1.3K citations · Full text

, , +16

Role of a Peptide Tagging System in Degradation of Proteins Synthesized from Damaged Messenger RNA

Kenneth C. Keiler, P R Waller, Robert T. Sauer · Science · 1996 · 1.1K citations

, , +17

Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

Timothy J. Kieffer, Christopher H.S. McIntosh, Raymond A. Pederson · Endocrinology · 1995 · 1.1K citations

, , +17

The ClpXP and ClpAP proteases degrade proteins with carboxy-terminal peptide tails added by the SsrA-tagging system

Susan Gottesman, Eric Roche, Yi Zhou et al. · Genes & Development · 1998 · 857 citations · Full text

, , +12

1–5 of 792

Authors

2.9K

  1. RT
    Ronald T. Borchardt

    University of Kansas, United States

    9 publications · 489 citations

    9

    h-index

  2. SC
    Steven Clarke

    University of California, Los Angeles, United States

    8 publications · 2.7K citations

    8

    h-index

  3. RA
    Richard A. Laursen

    Boston University, United States

    6 publications · 1.1K citations

    6

    h-index

  4. EM
    Elizabeth M. Topp

    University of Kansas, United States

    6 publications · 266 citations

    6

    h-index

  5. JK
    Jindŕich Kopec̆ek

    University of Utah, United States

    5 publications · 606 citations

    5

    h-index

1–5 of 2.9K

Institutions

823

  1. University of Kansas

    Lawrence, United States

    19 h-index

    65 publications

    4.6K citations

  2. Inserm

    Paris, France

    14 h-index

    53 publications

    2.3K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    61 publications

    2.3K citations

  4. Harvard University

    Cambridge, United States

    12 h-index

    32 publications

    3.5K citations

  5. Boston University

    Boston, United States

    12 h-index

    24 publications

    1.8K citations

  6. National Institutes of Health

    Bethesda, United States

    9 h-index

    30 publications

    2.7K citations

  7. University of British Columbia

    Vancouver, Canada

    9 h-index

    20 publications

    5.3K citations

  8. University of California, Los Angeles

    Los Angeles, United States

    9 h-index

    19 publications

    5.5K citations

1–8 of 823

Venues

  1. Journal of Biological Chemistry

    JBC · 49 publications · 8.2K citations

    35

    h-index

  2. European Journal of Biochemistry

    EJB · 24 publications · 1.7K citations

    18

    h-index

  3. FEBS Letters

    24 publications · 1.3K citations

    16

    h-index

  4. Pharmaceutical Research

    15 publications · 1.2K citations

    14

    h-index

  5. Biochemistry

    14 publications · 591 citations

    13

    h-index

1–5