Terrence L. Geiger

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation.

Terrence L. Geiger, Steven Clarke · Journal of Biological Chemistry · 1987 · 1.3K citations · Full text

Peptide Engineering, Glycobiology, Aspartyl Residues +16

Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia

Chihaya Imai, Keichiro Mihara, Martin Andreánsky et al. · Leukemia · 2004 · 806 citations

Hematological Malignancy, Mixed-phenotype Acute Leukemia, Malignant Blood Disorder +9

Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

Jun Wei, Lingyun Long, Wenting Zheng et al. · Nature · 2019 · 409 citations · Full text

Cancer Therapy, Cancer Immunosurveillance, Novel Therapy +9

Anti-TNF therapy in IBD exerts its therapeutic effect through macrophage IL-10 signalling

Pim J. Koelink, Felicia M. Bloemendaal, Bofeng Li et al. · Gut · 2019 · 217 citations · Full text

PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells

Wenting Zheng, Carol O’Hear, Rajshekhar Alli et al. · Leukemia · 2018 · 201 citations · Full text

Pi3k Orchestration, Signal Transduction, Immunology +8