Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Jun Wei, Lingyun Long, Kai Yang, +8

Nature Immunology

Cell AutophagyMitophagySignal TransductionAutoimmune DiseaseT-regulatory Cell +12

Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy

Jun Wei, Lingyun Long, Wenting Zheng, +14

Nature

Cancer TherapyCancer ImmunosurveillanceNovel TherapyImmunologyImmune Checkpoint Inhibitor +7

Lipid signalling enforces functional specialization of Treg cells in tumours

Seon Ah Lim, Jun Wei, Thanh-Long M. Nguyen, +9

Nature

Signal TransductionSignaling PathwayCell RegulationCell InteractionPathology +8

The inhibition of tumor growth and metastasis by self-assembled nanofibers of taxol

Huaimin Wang, Jun Wei, Chengbiao Yang, +4

Biomaterials

NanoparticlesNanomedicineEngineeringNanomaterialsTumor Growth +4

Coronary Smooth Muscle Differentiation from Proepicardial Cells Requires RhoA-Mediated Actin Reorganization and p160 Rho-Kinase Activity

Jun Lu, Thomas E. Landerholm, Jun Wei, +6

Developmental Biology

Cardiac MuscleCardiomyopathyMolecular PhysiologyMedicinePhysiology +10

Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants.

Linda M. Hendershot, Jun Wei, James R. Gaut, +3

Proceedings of the National Academy of Sciences

Protein SecretionProtein AssemblyMolecular BiologyDisulfide Bond FormationImmunoglobulin Folding +14

In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions

Hongling Huang, Peipei Zhou, Jun Wei, +13

Cell

Genome SurgeryImmune Cell DevelopmentImmunologyGenetic EngineeringGene Editing +6

Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine

Guotong Fu, Clifford S. Guy, Nicole M. Chapman, +20

Nature

InflammationPhysiologyAutophagyImmunologyCell Death +8

MicroRNA-21 activates hepatic stellate cells via PTEN/Akt signaling

Jun Wei, Lisha Feng, Li Zhong, +2

Biomedicine & Pharmacotherapy

HepatologyLiver PhysiologyMicrorna DetectionSmall RnaGene Expression +4

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Lingyun Long, Jun Wei, Seon Ah Lim, +24

Nature

T-regulatory CellImmunologyGenetic EngineeringNutrient LicensingT Cell Immunity +6