Kai Yang

mTORC1 couples immune signals and metabolic programming to establish Treg-cell function

Hu Zeng, Kai Yang, Caryn Cloer et al. · Nature · 2013 · 771 citations · Full text

Signal Transduction, Immune Dysregulation, Adaptive Immune System +15

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Jun Wei, Lingyun Long, Kai Yang et al. · Nature Immunology · 2016 · 467 citations · Full text

Cell Autophagy, Mitophagy, Signal Transduction +14

The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

Chengxian Xu, Shaogang Sun, Travis S. Johnson et al. · Cell Reports · 2021 · 459 citations · Full text

T Cell Exit from Quiescence and Differentiation into Th2 Cells Depend on Raptor-mTORC1-Mediated Metabolic Reprogramming

Kai Yang, Sharad Shrestha, Hu Zeng et al. · Immunity · 2013 · 382 citations · Full text

Signal Transduction, Th2 Cells Depend, Cell Division +12

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation

Haiyan Tan, Kai Yang, Yuxin Li et al. · Immunity · 2017 · 373 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +8