Concepedia

Paxx

PAXX is a protein cofactor in the non-homologous end joining pathway that specifically stabilizes the XRCC4–DNA ligase IV complex at DNA double-strand breaks to facilitate ligation.

24

Publications

2.5K

Citations

177

Authors

74

Institutions

Publications per year

2017–2026

8

Variants

Paralog Of Xrcc4 And Xlf

Parents

Publications

24

Pax: A murine multigene family of paired box-containing genes

Claudia Walther, Jean‐Louis Guénet, Dominique Simon et al. · Genomics · 1991 · 428 citations · Full text

, , +6

Crystal structure of a paired domain-DNA complex at 2.5 å resolution reveals structural basis for pax developmental mutations

Wenqing Xu, Mark A. Rould, Susie Jun et al. · Cell · 1995 · 326 citations · Full text

, , +9

PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

Takashi Ochi, Andrew N. Blackford, Julia Coates et al. · Science · 2015 · 302 citations · Full text

, , +17

The oncogenic potential of Pax genes.

Catharina C. Maulbecker · The EMBO Journal · 1993 · 245 citations · Full text

, , +14

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

Mengtan Xing, Mingrui Yang, Wei Huo et al. · Nature Communications · 2015 · 174 citations · Full text

, , +17

1–5 of 24

Authors

177

  1. SP
    Stephen P. Jackson

    The Gurdon Institute, United Kingdom

    4 publications · 603 citations

    4

    h-index

  2. TL
    Tom L. Blundell

    University of Cambridge, United Kingdom

    3 publications · 461 citations

    3

    h-index

  3. MX
    Mengtan Xing

    Norwegian University of Science and Technology, Norway

    3 publications · 243 citations

    3

    h-index

  4. AN
    Andrew N. Blackford

    University of Oxford, United Kingdom

    3 publications · 483 citations

    3

    h-index

  5. WJ
    Wenxia Jiang

    Columbia University, United States

    2 publications · 289 citations

    2

    h-index

1–5 of 177

Institutions

74

  1. University of Cambridge

    Cambridge, United Kingdom

    5 h-index

    31 publications

    4.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    19 publications

    1.3K citations

  3. Institut Pasteur

    Paris, France

    4 h-index

    16 publications

    2K citations

  4. University of Oxford

    Oxford, United Kingdom

    4 h-index

    5 publications

    819 citations

  5. The Gurdon Institute

    Cambridge, United Kingdom

    4 h-index

    18 publications

    2.8K citations

  6. Inserm

    Paris, France

    3 h-index

    16 publications

    1.1K citations

  7. Wellcome Sanger Institute

    Cambridge, United Kingdom

    3 h-index

    11 publications

    1.2K citations

  8. Wellcome Trust

    London, United Kingdom

    3 h-index

    15 publications

    2.4K citations

1–8 of 74

Venues

  1. Nature Communications

    3 publications · 323 citations

    3

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 154 citations

    2

    h-index

  3. FEBS Open Bio

    2 publications · 69 citations

    2

    h-index

  4. Cell Reports

    2 publications · 192 citations

    2

    h-index

  5. The EMBO Journal

    1 publications · 245 citations

    1

    h-index

1–5